3.0T磁共振腹部DWI序列定量评价腰椎骨质疏松的价值  

Value of abdominal diffusion-weighted imaging at 3.0 T MR in quantitatively evaluating esteoporosis of lumbar vertebral

作　　者：张恒[1,2] 黄刚[1] 毛泽庆[1] 左晓娜[1] 王平[1] 徐香玖[1] 

机构地区：[1]甘肃省人民医院放射科,甘肃兰州730000 [2]宁夏医科大学研究生院,宁夏银川750000

出　　处：《医学影像学杂志》2016年第6期1083-1087,共5页Journal of Medical Imaging

基　　金：甘肃省卫生行业科研计划项目(GSWSKY-2014-09)

摘　　要：目的探讨高分辨磁共振腹部弥散加权像(DWI)测量表观扩散系数(ADC)评价男、女性腰椎骨质疏松的价值。方法 63例受试者用双能X线吸收仪(DXA)测量腰1~4(L1-4)椎体骨密度(BMD)和DWI测量ADC值;男、女性L1-4各椎体ADC值与BMD值、平均ADC值与总BMD、T值、年龄分别行线性相关分析;男、女性分别按T值分为骨质正常组、减少组和疏松组,方差分析比较ADC值的差异;ROC曲线分别评价ADC值对男、女性L1-4椎体骨质疏松的诊断价值。结果 L1-4平均ADC值男性(0.320±0.190)×10-3mm^2/s与BMD、T值、年龄无相关性(r=0.033、0.038、-0.106,P>0.05),女性(0.281±0.091)×10-3mm^2/s与BMD、T值正相关(r=0.370、0.346,P﹤0.05),与年龄负相关(r=-0.54,P﹤0.01);三组间差异比较男性无统计学意义(P>0.05),女性有统计学意义(P﹤0.05);ROC曲线分析女性组有诊断意义,且L3水平曲线下面积(AUC=0.929)最大,男性组无意义。结论 ADC值对女性腰椎骨质疏松具有一定的诊断价值。Objective To explore the value of the apparent diffusion coefficient（ ADC） in abdominal high-resolution diffusion-weighted MR Imaging in evaluating the lumbar vertebral osteoporosis of the male and female. Methods 63 subjects were measured the bone mineral density（ BMD） by dual energy X-ray absorptiometry and ADC by abdominal MR Imaging at the site of lumbar spine（ L1-4）. Linear correlation was applied to analyze the relationship between the ADC and BMD values of every L1-4vertebral,the average of ADC values and total BMD,T score and age of Male and female,respectively. Males and females were divided into normal,osteopenia and osteoporosis groups based on the T score respectively,variance analysis was used for ADC comparison between groups. The receiver-operating characteristic（ ROC） curve was used to evaluate the diagnostic value of osteoporosis at L1-4by ADC for male and female respectively. Results No significant correlation was present between the average of ADC 〔（ 0. 320 ± 0. 190） × 10-3mm^2/ s〕at L1-4and BMD,T score,age（ r = 0. 033,0. 038,0. 033,P〈0. 05） in male group.But there was a positive correlation between average of ADC 〔（ 0. 281 ± 0. 091） × 10-3mm^2/ s〕at L1-4and BMD,T score（ r =0. 370,0. 346,P ﹤ 0. 05） in female group,and a negative correlation with the age（ r =-0. 54,P ﹤ 0. 01）. There was no statistically significant difference among the three male groups（ P〈0. 05）,and a statistical significance difference among the three female groups（ P ﹤ 0. 05）. ROC curve analysis showed that female group had a good diagnostic value,and area under curve（ AUC = 0. 929） of L3 was the largest,there was no value in male group. Conclusion To a certain extent,ADC has diagnostic value of lumbar vertebral osteoporosis for women.

关 键 词：磁共振成像 骨密度 弥散加权像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681[医药卫生—诊断学]