中国住院患者急性肾损伤流行病学调查现状  

Epidemiology of acute kidney injury in hospitalized patients in China

作　　者：郎夏冰 杨毅[1] 陈江华[1] 

机构地区：[1]浙江大学医学院附属第一医院肾脏病中心

出　　处：《浙江大学学报（医学版）》2016年第2期208-213,共6页Journal of Zhejiang University(Medical Sciences)

基　　金：“十二五”国家科技支撑计划(2011BAI10B07)

摘　　要：急性肾损伤是影响住院患者住院时间、预后以及医疗费用的重要疾病之一，涵盖从轻度血肌酐升高到肾功能衰竭需要替代治疗的一系列疾病谱。随着对疾病重视程度的提高，相关流行病学研究也越来越多，尤其是近年来，国内一些高质量的大样本、多中心研究成果陆续发表。但是，由于地区经济发展水平及目标人群、客观观察指标的选择和检测、基于急性肾损伤诊断定义的研究策略等的不同，住院患者急性肾损伤流行病学研究的结果仍有较大异质性，国内报道的急性肾损伤发病率明显低于发达国家。本文对中国住院患者急性肾损伤的流行病学研究现况和存在的问题进行了分析，旨在引起临床和相关卫生工作系统人员的重视，为设计更加客观的流行病学研究策略提供借鉴，以期获得详实的流行病学数据，为实现中国急性肾损伤的零病死率计划而努力。Acute kidney injury （AKI） is a disease spectrum ranging from minimal elevation of serum creatinine to complete renal failure. It is significantly associated with increased mortality, length of hospital stay and medical care cost. With the increasing awareness of the importance of AKI, several high quality and muhicenter epidemiological studies have been published recently in China. However, the results differ a lot due to the differences in regional economic development, the selection of target population and testing indicators, the disease definition and study strategies. The reported incidence of AKI in China is much lower than that in the developed countries. This article will analyze the current status and the problems facing AKI epidemiological studies of hospitalized patients with our own data and those from literature. The article intends to clarify the burden of AKI, to increase the awareness of AKI among clinicians and policy makers for achieving the goal of ＂zero by 2025＂ in China.

关 键 词：肾/损伤 急性病 流行病学 数据收集 综述 

分 类 号：R692[医药卫生—泌尿科学]