异丙酚靶控输注在宫腔镜手术中的应用效果  

Propofol TCI in hysteroscopy Operation of the application of clinical effect observation

作　　者：范卫英[1] 刘颖[1] 

机构地区：[1]福建医科大学附属龙岩市第一医院麻醉科,龙岩市364000

出　　处：《微创医学》2016年第3期351-353,共3页Journal of Minimally Invasive Medicine

摘　　要：目的观察宫腔镜手术中使用异丙酚靶控输注的安全性及可行性。方法选择接受宫腔镜手术的患者80例,随机分成对照组和观察组。静脉注射2μg/kg芬太尼后,对照组给予静脉推注异丙酚2 mg/kg后以80~150μg/kg·min静脉恒速输注维持麻醉;观察组进行靶控输注（TCI）系统给药,最初以2μg/m L作为标准浓度,行宫颈扩张时增加到4.7μg/m L,然后将靶浓度设置在3.3μg/m L至手术结束。结果两组异丙酚用量比较,差异无统计学意义（P〉0.05）;观察组意识消失时间、苏醒时间、平均动脉压（MAP）、心率（HR）、血氧饱和度（SpO_2）均高于对照组,差异有统计学意义（P〈0.05）。结论运用异丙酚TCI进行宫腔手术麻醉比静脉恒速输注具有意识消失时间短、苏醒快、生命征更平稳等优点。Objective To observe the safety and feasibility of propofol TCI in hysteroscopic surgery.Methods A total of 80 patients with hysteroscopy were randomly divided into control group and observation group. After intravenous injection of 2 g / kg fentanyl,the control group was given intravenous injection of propofol 2 mg / kg to 80- 150 μg / kg · min intravenous infusion to maintain constant speed anesthesia;Observation group were administered TCI system with initially 2 μg / m L plasma concentration as the standard,to 4. 7 μg / m L when cervical dilation,then rake concentration provided at 3. 3μg / m L to the end of surgery.Results The amount of propofol between the two groups was not statistically significant（ P 0. 05）; The unconsciousness time,recovery time,MAP,HR,SpO_2 of the observation group were higher than those of control group,the differences were statistically significant（ P 0. 05）. Conclusion propofol TCI used to anesthesia intrauterine operation have the advantage of rapid hypnogigia,rapid recovery and more smooth of vital sign than intravenous infusion.

关 键 词：异丙酚 靶控输注 静脉输注 宫腔镜手术 

分 类 号：R614[医药卫生—麻醉学]