普鲁兰乙酸酯水凝胶的制备及性能  

Preparation and Properties of Pullulan Acetate Hydrogel

作　　者：陈洁[1,2] 白林[1,2] 吕亚娟[1] 王昌[1] 张鹏升[1] 

机构地区：[1]兰州城市学院化学与环境学院,甘肃兰州730070 [2]兰州城市学院绿色化学实验与教学研究所,甘肃兰州730070

出　　处：《化学世界》2016年第6期338-341,共4页Chemical World

摘　　要：水凝胶在最近的几十年里,因为它们自组装形成的独特三维网络结构和性能而获得重视。水凝胶已在农业、工业、医学、石油化工、日用品和化妆品等领域具有广阔的应用前景。多糖酯及其衍生物具有易于形成特殊的高级结构的性质,可制备水凝胶。利用普鲁兰多糖的特性,合成了普鲁兰乙酸酯水凝胶(PAH),并对其溶胀率(SR)以及载药量、药物释放量进行了研究。结果表明普鲁兰乙酸酯水凝胶具有大量的微孔结构,具有较好的保水性,凝胶在碱性条件下具有较好的载药性,酸性环境下有较好的释药性能。Hydrogels have received considerable attention over recent years because they exhibit interesting self-assembly phenomena,forming three-dimensional networks.Hydrogels have a broad application prospect in agriculture,industry,medicine,petroleum chemical industry,daily necessities,cosmetics and so on.The synthesis and properties of pullulan acetate were studied.The results showed that pullulan acetate hydrogel had good drug loading property in alkaline solution and good release property in acidic sdution.Scanning electron microscopy was used to characterize the gel,showing that the hydrogel had a network structure with large number of micropores.

关 键 词：水凝胶 普鲁兰乙酸酯 溶胀率 控制释放 

分 类 号：TB34[一般工业技术—材料科学与工程] O636[理学—高分子化学]