Developmental process of the arcuate fasciculus from infancy to adolescence: a diffusion tensor imaging study  

作　　者：Hyeong Jun Tak Jin Hyun Kim Su Min Son 

机构地区：[1]Department of Physical Medicine and Rehabilitation, School of Medicine, Yeungnam University

出　　处：《Neural Regeneration Research》2016年第6期937-943,共7页中国神经再生研究（英文版）

基　　金：supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,Science and Technology,No.2012-013997

摘　　要：We investigated the radiologic developmental process of the arcuate fasciculus（AF） using subcomponent diffusion tensor imaging（DTI） analysis in typically developing volunteers. DTI data were acquired from 96 consecutive typically developing children, aged 0–14 years. AF subcomponents, including the posterior, anterior, and direct AF tracts were analyzed. Success rates of analysis（AR） and fractional anisotropy（FA） values of each subcomponent tract were measured and compared. AR of all subcomponent tracts, except the posterior, showed a significant increase with aging（P 〈 0.05）. Subcomponent tracts had a specific developmental sequence： First, the posterior AF tract, second, the anterior AF tract, and last, the direct AF tract in identical hemispheres. FA values of all subcomponent tracts, except right direct AF tract, showed correlation with subject＇s age（P 〈 0.05）. Increased AR and FA values were observed in female subjects in young age（0–2 years） group compared with males（P 〈 0.05）. The direct AF tract showed leftward hemispheric asymmetry and this tendency showed greater consolidation in older age（3–14 years） groups（P 〈 0.05）. These findings demonstrated the radiologic developmental patterns of the AF from infancy to adolescence using subcomponent DTI analysis. The AF showed a specific developmental sequence, sex difference in younger age, and hemispheric asymmetry in older age.We investigated the radiologic developmental process of the arcuate fasciculus（AF） using subcomponent diffusion tensor imaging（DTI） analysis in typically developing volunteers. DTI data were acquired from 96 consecutive typically developing children, aged 0–14 years. AF subcomponents, including the posterior, anterior, and direct AF tracts were analyzed. Success rates of analysis（AR） and fractional anisotropy（FA） values of each subcomponent tract were measured and compared. AR of all subcomponent tracts, except the posterior, showed a significant increase with aging（P 〈 0.05）. Subcomponent tracts had a specific developmental sequence： First, the posterior AF tract, second, the anterior AF tract, and last, the direct AF tract in identical hemispheres. FA values of all subcomponent tracts, except right direct AF tract, showed correlation with subject＇s age（P 〈 0.05）. Increased AR and FA values were observed in female subjects in young age（0–2 years） group compared with males（P 〈 0.05）. The direct AF tract showed leftward hemispheric asymmetry and this tendency showed greater consolidation in older age（3–14 years） groups（P 〈 0.05）. These findings demonstrated the radiologic developmental patterns of the AF from infancy to adolescence using subcomponent DTI analysis. The AF showed a specific developmental sequence, sex difference in younger age, and hemispheric asymmetry in older age.

关 键 词：tracts tensor younger older developmental maturation typically asymmetry anisotropy fractional 

分 类 号：R445.2[医药卫生—影像医学与核医学] R339.3[医药卫生—诊断学]