超选择动脉栓塞后手术切除颈动脉体瘤的疗效分析  

Efficacy analysis of superselective embolization followed by surgical resection for carotid body tumors

作　　者：张建彬[1,2] 徐荣伟[1,2] 陈洁[1] 孔杰 叶志东[1] 刘鹏[1,2] 

机构地区：[1]中日友好医院心脏血管外科,北京100029 [2]北京协和医学院研究生院,北京100730

出　　处：《中国普通外科杂志》2016年第6期859-863,共5页China Journal of General Surgery

基　　金：科技部国家国际科技合作专项基金资助项目(2013DFA31900)

摘　　要：目的:探讨超选择动脉栓塞后手术切除颈动脉体瘤的疗效。方法:回顾中日友好医院自2007年4月―2015年9月手术治疗的26例颈动脉体瘤患者临床资料,分析其临床特点、影像学检查、治疗及预后情况,根据是否进行术前超选择栓塞分为栓塞组(9例)和未栓塞组(17例),分析并比较两组患者的相关临床指标。结果:26例(27侧)共进行26侧手术治疗。与未栓塞组比较,栓塞组平均手术时间(127.22 min vs.158.82 min)和平均出血量(110.00 m L vs.355.88 m L)均明显减少(均P<0.05),但两组的手术时间与出血量均随患者肿瘤严重程度(Shamblin分型)增加而成升高趋势。26例手术患者术后颈部肿物均消失,术前伴有疼痛及咽部不适者术后症状均消失,围手术期无死亡及肢体瘫痪,术后神经功能障碍7例(26.92%),均于术后6个月随访时恢复。结论:手术切除颈动脉体瘤安全可靠,是颈动脉体瘤的首选治疗,而术前超选择栓塞可以明显减少出血量,缩短手术时间。Objective：To evaluate the effcacy of superselective embolization followed by surgical resection in treatment of carotid body tumors. Methods：hTe clinical data of 26 patients with carotid body tumors treated in China-Japan Friendship Hospital from April 2007 to September 2015 were reviewed. According to whether or not they underwent preoperative superselective embolization, the patients were classiifed into embolization group （9 cases） and non-embolization group （17 cases）. hTe relevant clinical variables of the two groups of patients were analyzed and compared. Results：Surgical resection was performed in 26 sides of the 26 patients （27 sides）. In embolization group compared with non-embolization group, the mean operative time （127.22 min vs. 158.82 min） and intraoperativeblood loss （110.00 mL vs. 355.88 mL） were both significantly reduced （both P〈0.05）, while both operative time and intraoperative blood loss presented an increasing tendency with increase of the severity of the tumor （Shamblin’s classiifcation） in either group. In all the 26 patients, the neck mass disappeared and the accompanied symptoms such as pain and pharyngeal discomfort were relieved after surgery. No death or paralysis occurred during perioperative period, but nervous dysfunction occurred in 7 patients （26.92%） and, in all of them, it had recovered on follow-up 6 months atfer surgery. Conclusion：For carotid body tumors, surgical resection is safe and reliable, and is the ifrst choice of treatment. Preoperative superseclective embolization can signiifcantly reduce blood loss and shorten operative time.

关 键 词：颈动脉体瘤 栓塞 治疗性 血管造影术 

分 类 号：R654.3[医药卫生—外科学]