急性颅脑损伤后垂体激素变化规律研究  

Study on the Changes of Pituitary Hormones in Patients with Acute Craniocerebral Injury

作　　者：蔡琦[1] 傅剑川 陈隆益[1] 

机构地区：[1]乐山市五通桥区人民医院,四川乐山614800

出　　处：《中外医学研究》2016年第17期21-23,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究急性颅脑损伤后患者垂体激素的变化规律。方法:选取2013年5月-2015年5月于笔者所在医院接受治疗的80例急性颅脑损伤患者,设为观察组;同期的80例健康体检者设为对照组,分别于患者入院时、3 d、7 d后采集静脉血样,检测促黄体生成素(LH)、卵泡刺激素(FSH)和促甲状腺激素(TSH)的动态变化情况。结果:入院时观察组患者LH高于对照组,TSH低于对照组,差异有统计学意义(P<0.05);入院时观察组重型患者的LH与FSH均高于轻型和中型患者,差异有统计学意义(P<0.05);观察组死亡患者入院时的FSH、LH及TSH均高于残疾和预后良好患者,差异有统计学意义(P<0.05)。结论:急性颅脑损伤患者的FSH、LH及TSH等垂体激素会发生变化,损伤程度越严重,激素水平越高,在动态观察过程中水平下降,其动态变化值与基础值能够用于评价伤情与判断预后。Objective：To explore the changes of pituitary hormones in patients with acute craniocerebral injury.Method：From May 2013 to May 2015,80 patients with acute craniocerebral injury treated in this hospital were selected as the observation group,80 cases of healthy persons were selected in the same period as the control group.The venous blood samples at the time of admitted to the hospital,3 days later,7 days later were collected,and luteinizing hormone（LH）,follicle stimulation hormone（FSH） and promoting thyroid hormone（TSH） dynamic change situation were detected.Result：Admitted to the hospitd,LH in the observation group was higher than that in the control group,TSH was lower than that in the control group,the differences were significant（P〈0.05）.The FSH and LH of the heavy patients in the observation group were higher than those of light and medium patients（P〈0.05）,the FSH,LH and TSH of the died patients in the observation group were significantly higher than the disability and prognosis patients,the differences were significant（P〈0.05）.Conclusion：The pituitary hormones such as FSH,LH and TSH in patients with acute craniocerebral injury will be changed.The more severe the injury,the higher the level of hormone,the value of dynamic changes and basic values can be used to evaluate the effect of injury and prognosis.

关 键 词：急性颅脑损伤 垂体激素 变化规律 

分 类 号：R651.15[医药卫生—外科学]