3D-FSE Cube序列在垂体微腺瘤诊断中的应用价值  

Evaluation of 3D-FSE Cube sequence in diagnosis of pituitary micro-adenoma

作　　者：于春英[1,2] 颜林枫[1] 刘志成[1] 韩宇[1] 胡玉川[1] 李刚锋[1] 于 瀛[1] 孙倩[1] 王文[1] 崔光彬[1] 

机构地区：[1]第四军医大学唐都医院放射科,陕西西安710038 [2]西安医学院第一附属医院影像科

出　　处：《实用放射学杂志》2016年第6期829-832,共4页Journal of Practical Radiology

基　　金：陕西省社发攻关课题（2012K13-02-27）.

摘　　要：目的 评价3D-FSE Cube序列对垂体微腺瘤的诊断价值。方法 对47例垂体微腺瘤的2D-FSE、3D-FSE Cube序列图像进行评分，评价指标如下：①病变与正常垂体的分界；②正常垂体与海绵窦分界；③垂体柄显示；④总体图像质量；⑤磁化率伪影。并计算2组检出率。图像评分应用Wilcoxon符号秩检验。评价者间一致性采用Kappa值表示。P＜0.05有统计学意义。结果3D-FSE Cube序列在图像质量方面优于2D-FSE序列（P＜0.05），T1WI的磁化率伪影明显比2D-FSE序列少（P＜0.01）。3D-FSE Cube、2D-FSE序列对垂体微腺瘤的总检出率分别为100%（47/47）、85.1%（40/47），其中T1WI的检出率分别为97.9%（46/47）、57.4%（27/47）。评价者间一致性较高，T1WI、T2WI的k值分别为0.86、0.88。结论3D-FSE Cube序列显示垂体微腺瘤明显优于2D-FSE序列，扫描时间缩短20~27 s，具有重要的临床应用价值。Objective To assess the value of 3D-FSE Cube sequence in diagnosis of pituitary micro-adenoma. Methods 3D-FSE Cube as well as 2D-FSE images of the pituitary were acquired in 47 patients with known pituitary micro-adenoma. Two experienced radiologists evaluated the images quality by the following criteria： ①the border between the pituitary gland and the lesion ; ②boundary edge of the cavernous sinus and pituitary gland; ③visualization of the pituitary stalk; ④overall image quality; ⑤ susceptibility artifacts. The detection rates in two groups were calculated and analyzed statistically. Qualitative analyses were accomplished by Wilcoxon signed-rank test. The interobserver agreement assessment was analyzed with K-statistics. P〈0.05 was considered to have a statistically significant difference. Results The image quality of 3D-FSE Cube sequence is better than that of 2D-FSE sequence （P〈0. 05）, and T1-weighted imaging （T1N I） showed fewer susceptibility artifacts in 3D-FSE Cube sequence （P〈0. 01）. The detection rates of 3D-FSE Cube and 2D-FSE were 100% （47/47）, 85.1% （40/47）, respectively, of which on T1WI were 97.9% （46/47）, 57.4% （27/47）. The results of the two observers were in a great agreement on T1WI （k=0.86） and T2WI （k=0.88）. Conclusion 3D-FSE Cube sequence with superior image quality,of which the scan time decreased about 20-27 s, is proved to be an available clinical detection of pituitary micro-adenoma.

关 键 词：垂体微腺瘤 磁共振成像 3D-FSE CUBE 2D-FSE 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]