实验兔肝脏体素内不相干运动-扩散加权成像与CT灌注参数的相关性探讨  

The correlation of intravoxel incoherent motion diffusion-weighted imaging and CT perfusion in normal rabbit liver

作　　者：钟志伟[1] 何建勋[1] 李新春[1] 邓宇[1] 万齐[1] 邹乔[1] 邓颖诗[1] 余煜栋 

机构地区：[1]广州医科大学附属第一医院放射科,广东广州510120

出　　处：《实用放射学杂志》2016年第6期955-958,共4页Journal of Practical Radiology

基　　金：广东省医学科研基金项目（A2015390）;广州市科技计划项目（201510010234）.

摘　　要：目的 探讨正常实验兔肝脏的体素内不相干运动-扩散加权成像（IVIM-DWI）与CT灌注成像灌注参数之间的相关性。方法 对8只健康新西兰大白兔肝脏分别行IVIM-DWI及CT灌注扫描，分别生成IVIM-DWI的假扩散系数（D＊）和灌注分数（f）以及CT灌注成像的血流量（BF）和血容量（BV）。对BF和D＊，BV和f行Pearson相关性分析。结果 正常实验兔肝脏的D＊为（34.61±8.5）×10-3m2/s，f为（30±8）%。BF为（27.76±4.59） mL·100 mL-1·min-1，BV为（9.2±2.2） mL/100 mL。 BF和D＊，BV和f的相关系数分别为0.155和0.018，相伴概率分别为0.222和0.886，2组参数之间均无明显的相关性。结论 正常实验兔肝脏的CT灌注成像和IVIM-DWI参数中，BF和D＊、BV和f之间没有明确的相关性。Objective To probe the correlation between intravoxel incoherent motion （IVIM） DWI and CT perfusion parameters. Methods 8 healthy New Zealand white rabbits underwent IVIM and CT perfusion respectively. IVIM parameters including pseudo diffusion coefficient D＊ and perfusion fraction f, and CT perfusion parameters including BF and BV were calculated. The correlations were analyzed using Pearson method. Results D＊ and f values of normal rabbit liver were （34. 61 ± 8. 5） × 10-3 mm2/s and 130-V 8）%, meanwhile the BF and BV were （27. 76±4.59） mL · 100 mL-1 ·min-1 and （9.2±2.2） mL/100 mL, respectively. The correlation coefficient between BF and D＊ , and between BV and f were 0. 155 and 0. 018 with the P value of 0. 222 and 0. 886, respectively. No significant correlation was found between the two groups. Conclusion There are no definitely correlations between BF and D＊ and between BF and f value in normal rabbit liver.

关 键 词：体素内不相干运动 扩散加权成像 计算机体层成像 

分 类 号：R322.47[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]