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机构地区:[1]上海交通大学附属第一人民医院临床药学科,上海200080
出 处:《药品评价》2016年第6期24-27,共4页Drug Evaluation
摘 要:目的:了解近年来上海样本医院抗感染用药变化趋势,供科研、生产、销售和使用部门参考。方法:采用2011~2013年上海119家样本医院抗感染用药数据,统计大类和品种的金额、份额、增长率、复合年均增长率等,结合临床应用的情况进行分析和讨论。结果:近年来政府采取一系列深化医疗改革的措施,并对不合理应用抗菌药物开展专项整治活动,上海样本医院抗感染用药上升势头得到明显遏制,增长率远低于全部用药。第三、第四代头孢菌素和喹诺酮类等使用比例下降,青霉素类、第一代头孢菌素等使用比例上升,中成药使用增多,呈现良好的发展态势,抗菌药物整治初显成效。结论:抗感染药物是最常用的药物之一,应继续加强药政管理,合理应用,减缓细菌耐药性的产生和发展。Objective: To investigate the trend of antibiotics in Shanghai sample hospitals in recent years and provide information as reference to drug manufacturing, sale and use industries.Methods: The data of antibiotics gathered in 119 Shanghai sample hospitals during 2011~2013 included sales amount, proportion, growth rate, CAGR%, etc. We analyzed the data according to clinical application.Results: The government carries out a series of health care reform and special rectification of irrational antibiotics use in recent years. The rising of antibiotics use was reduced obviously in Shanghai sample hospitals. The growth rate of antibiotics was by far lower than all of the drugs. The proportion of third-generation cephalosporins, fourth-generation cephalosporins and quinolone use has declined. The proportion of penicillins and first-generation cephalosporins use has increased. The Chinese traditional drugs have been used increasingly. The special rectification of irrational antibiotics showed early Results.Conclusion:Antibiotics are widely used. We must continue to strengthen drug administration and promote rational use of drugs in order to reduce the occurrence and development of bacterial drug resistance.
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