常规不规则红细胞血型检测分析  

Detection and Analysis of Blood Group of Irregular Red Blood Cells

作　　者：田宗斌[1] 关茵[1] 

机构地区：[1]河南省焦作市中心血站,河南焦作454100

出　　处：《中国卫生产业》2016年第10期110-112,共3页China Health Industry

摘　　要：目的对常规不规则红细胞血型的检测进行分析。方法选取80例患者作为该次观察对象,均为2015年3月—2016年3月在该院进行治疗的患者,对其应用微柱凝胶抗球蛋白技术对不规则红细胞血型抗体进行分析,分析不同治疗患者中红细胞不规则血型的检出率以及产生规律。对检验出不规则红细胞血型的患者应用相容红细胞输血。对检验出lg G不规则血型的孕妇,当分娩时检测新生儿血型血清学,分析出孕妇血浆不规则抗体与新生儿溶血病的联系。对于检验出非特异性红细胞自身抗体的患者,对诊断结果与抗体的联系进行分析。最后进行不规则抗体的筛查检验以及Ig抗体与37℃反应性检查。结果 80例患者中不规则抗体15例(18.75%),其中有妊娠史或输血史的患者及女性患者所占比例多于无妊娠史或输血史及男性患者,其差异有统计学意义(P<0.05);15例不规则抗体的患者中特异性抗体以抗-M居多(40.00%),显著高于其他类型的抗体,其差异有统计学意义(P<0.05);15例不规则抗体的患者中抗体类型为Ig M(53.33%)显著高于其他类型抗体,且37℃反应阳性中特异性抗体以抗-M居多(46.67%),显著高于其他类型的抗体,其差异有统计学意义(P<0.05)。结论通过本次试验调查显示,有妊娠史或输血史的患者不规则抗体的检出率较高,且特异性抗体中以抗-M居多,它可以在初期检测新生儿溶血病以及安全输血产生重大意义,值得应用与推广。Objective The detection of irregular red blood cell blood group was analyzed. Methods A total of 80 cases of patients as the observation object, 2015 March 1, 2016 March 1, in a tertiary hospital in the city of treated patients, the application of micro column gel anti globulin technique of irregular RBC blood group antibody analysis, analysis different treatment in patients with red cell blood group irregular detection rate, and generate rules. To examine patients with irregular red blood cells in the blood compatibility of red blood cell transfusion. To test lg G irregular blood group of pregnant women, when childbirth neonatal serological detection, analysis of maternal plasma irregular antibody and hemolytic disease of the newborn contact. For the test of non specific red cell autoantibodies in patients on the diagnosis results of antibody and contact analysis. Finally, the screening test of irregular antibody and the reaction between Ig antibody and 37 degree centigrade were performed. Result 80 cases of patients not irregular antibody 15 cases（18.75%）, including pregnancy or blood transfusion history of patients and female patients accounted for more than non pregnancy history or history of blood transfusion and male patients, the difference has statistical significance（P 〈0.05）; 15 cases of irregular antibodies in patients with specific antibody against-M, the majority（40%） was significantly higher than that of other types of antibodies,the difference was statistically significant（P〈0.05）; 15 cases of irregular antibodies in patients with antibody Ig M（53.33%）was significantly higher than that of other types of antibody and 37 DEG C to react positive specific antibody to anti-M mostly（46.67%）, significantly higher than other types of antibodies, the difference has statistical significance（P〈 0.05）.Conclusion Through the test investigation shows that, pregnancy or blood transfusion history of irregular antibodies of patients with a high detection rate and specific antibody

关 键 词：不规则抗体 血型 红细胞 

分 类 号：R446[医药卫生—诊断学]