贵金属纳米颗粒杂化囊泡的制备及拉曼增强效果研究  

Preparation of Hybrid Polymer Vesicles Coated with Noble Metal Nanoparticles and Their SERS Effect

作　　者：王洁[1] 李惠梅[1] 倪云洲[1] 周永丰[1] 颜德岳[1] 

机构地区：[1]上海交通大学化学化工学院,上海200240

出　　处：《高分子学报》2016年第7期971-978,共8页Acta Polymerica Sinica

基　　金：国家重点基础研究发展计划(973计划;项目号2013CB834506);国家杰出青年基金(基金号21225420);国家自然科学基金(基金号21404070;91127047)资助项目

摘　　要：以超支化聚合物囊泡为模板制备了贵金属纳米颗粒表面功能化的杂化囊泡.模板囊泡通过多巴胺修饰的超支化聚醚HSP-DA在水中自组装形成.在碱性条件下,囊泡表面的多巴胺自聚合生成聚多巴胺,实现囊泡的交联.由于聚多巴胺具有强黏附特性,因此可以将HSP-PDA交联囊泡分别与Au纳米溶胶、Ag纳米溶胶直接混合,得到Au纳米颗粒或Ag纳米颗粒功能化的杂化囊泡.分别测定了2种杂化囊泡的拉曼光谱,发现杂化囊泡产生了明显的表面增强的拉曼光谱(SERS)信号,清晰显示了对应于囊泡模板分子的拉曼信号,表明可以通过SERS来原位检测囊泡的组成.Ag纳米颗粒杂化囊泡展示出更高的SERS灵敏度,可进一步作为探针检测水中浓度为10-7mol/L罗丹明6G分子,得到了显著增强的拉曼光谱,证明所制备的Ag纳米颗粒杂化囊泡可用于目标分子的痕量检测.Hybrid vesicles were prepared through surface-functionalization of hyperbranched polymer vesicles with noble metal nanoparticles. The vesicles were self-assembled from an amphiphilic hyperbranched polyether modified with dopamine groups at the terminal （HSP-DA）. The dopamine groups can self-polymerize in alkaline aqueous solution, leading to the crosslinking of HSP-DA vesicles. Due to the strong adhesion characteristics of polydopamine,the Au nanoparticles （AuNPs） or Ag nanoparticles （AgNPs） hybrid vesicles can be obtained through mixing the so-formed HSP-PDA crosslinked vesicles and AuNPs or AgNPs together. The formation of AuNPs hybrid vesicles and AgNPs hybrid vesicles was confirmed through transmission electron microscope （TEM） and ultraviolet-visible （UV-Vis） spectroscopy measurements. The Raman spectra of hybrid vesicles showed a significant enhancement of the Raman signals of the ether bond （1280 cm-1 ,1140 cm-1） and aromatic rings （ 1590 cm-1 ） that was attributed to the components of HSP-PDA vesicles compared to the barely visible Raman signals from HSP-PDA vesicles. In other words, it could be used to in situ detect the vesicle components by using surface-enhanced Raman scattering （SERS） of the AuNPs or AgNPs hybrid vesicles. In addition, AgNPs hybrid vesicles were further used as SERS probes to detect Rhodamine 6G molecules with a concentration of 10-7 mol/L in the aqueous solution. In the Raman spectrum, the Raman signals of C--C stretching vibration （ 1311 , 1361 , 1508,1572 and 1648 cm -1 ） , the C--H stretching vibration （772,921 and 1126 cm-1） ,and C--H in-plane bending vibration （1183 cm-1） from Rhodamine 6G can be recognized clearly, indicating the potentials of the as-prepared hybrid vesicles in trace detection.

关 键 词：金纳米颗粒 银纳米颗粒 囊泡 多巴胺 表面增强拉曼光谱 

分 类 号：O657.37[理学—分析化学]