浓缩生长因子联合Bio-oss骨粉促进骨缺损愈合的实验研究  

The Study of the Concentrated Growth Factors and Bio-oss Bone Meal on Promoting the Healing of Bone Defect

作　　者：牛临生[1] 解军军[1] 

机构地区：[1]临汾市人民医院口腔科,山西临汾041000

出　　处：《中国医药指南》2016年第16期17-18,共2页Guide of China Medicine

摘　　要：目的探究浓缩生长因子(concentrated growth factors,CGF)联合Bio-oss骨粉是否能促进骨缺损的愈合。方法选择新西兰白兔16只,在它们的颅盖骨上分别制备2个直径为3 mm圆形骨缺损。实验组:在制备的骨缺损处植入CGF+Bio-oss骨粉,对照组只植入Bio-oss骨粉,于术后4、8周,取标本,并从大体、X线、组织学等方面观察骨缺损的愈合情况。采用SPSS17.0软件对数据进行统计学分析。结果实验组骨缺损愈合的效果明显高于对照组,两组相比差异有统计学意义(P<0.05)。结论浓缩生长因子联合Bio-oss骨粉能明显促进骨缺损的愈合,缩短愈合时间。Objective To investigate the concentrated growth factors and Bio-oss bone meal on promoting the healing of bone defect. Methods Selecting sixteen New Zealand white rabbits, each of whose cranium bones were performed two round, 3 mm diameter, bone defects. The experimental group： the concentrated growth factors（CGF） and Bio-oss bone meal were implanted around the prepared bone defect. Control group： only implant Bio-oss bone meal. At the 4, 8 weeks, to observe the healing of bone defect by the shape, histology and X-Ray. Statistical analysis was conducted for the data by SPSS17.0 software. Results The experimental group was better than the control group. There were statistical significance between the experimental group and control group（P〈0.05）. Conclusion CGF and Bio-oss bone meal can facilitate the healing of bone tissue defect and Shorten the healing time.

关 键 词：浓缩生长因子(CGF) 骨缺损 骨愈合 

分 类 号：R683[医药卫生—骨科学]