三维圆周应变评价早期慢性肾病患者左心室心肌收缩功能变化  

Three-dimensional circumferential strain in evaluating changes of left ventricular myocardial contractional function in early chronic kidney disease patients

作　　者：刘开薇 任卫东[1] 孙璐[1] 宋光[1] 刘慧[1] 

机构地区：[1]中国医科大学附属盛京医院超声科,辽宁沈阳110004

出　　处：《中国介入影像与治疗学》2016年第7期421-425,共5页Chinese Journal of Interventional Imaging and Therapy

基　　金：辽宁省科技厅科学技术计划项目(2013225049)

摘　　要：目的采用三维整体圆周应变(GCS)评价早期慢性肾病(CKD)患者左心室心肌收缩功能。方法选取26例CKD2期患者(CKD2期组)、20例CKD3期(CKD3期组)患者及30名健康志愿者(对照组)。对所有受检者行常规二维超声心动图和三维斑点追踪成像(3D-STE),测量并比较常规超声心动图指标,包括左心室舒张末期间间隔厚度(IVSTd)、左心室舒张末期内径(LVEDd)、左心室舒张末期后壁厚度(LVPWTd)、左心室舒张末期容积(EDV)和收缩末期容积(ESV),以及3D-STE指标,包括三维左心室射血分数(3D-LVEF)、三维左心室心肌质量指数(3D-LVMi)及左心室GCS。结果与对照组比较,CKD2期组的IVSTd增大,LVEDd、GCS减小;CKD3期组的IVSTd、LVESV、3D-LVMi增大,LVEDd、3D-LVEF、GCS减小;与CKD2期组比较,CKD3期组的IVSTd、3D-LVMi增大,LVEDd、GCS减小,以上差异均有统计学意义(P均<0.05)。结论早期CKD患者左心室心肌收缩功能已减低,可通过GCS进行评价。Objective To assess the early changes of left ventricular myocardial contractional function in early chronic kidney disease （CKD） patients with three-dimensional global circumferential strain （GCS）. Methods Twenty-six cases of CKD2 group, 20 cases of CKD3 group and 30 cases of healthy subjects as control group were selected. Parameters of two-dimensional echocardiography including left ventricular at end-diastole diameter （LVEDd）, interventricular septal thickness at end-diastole （IVSTd）, left ventricular posterior wall thickness at end-diastole （LVPWTd）, end-diastolic volume （EDV）, end-systolic volume （ESV）, and parameters of 3D-STE including three-dimensional left ventricular ejection fraction （3D-LVEF）, three-dimensional left ventricular mass index （3D-LVMi）, and GCS were calculated and compared. Results Compared with the control group, IVSTd increased and LVEDd, GCS decreased in CKD2 group, IVSTd, LVESV, 3D-LVMi increased and LVEDd, 3D-LVEF, GCS decreased （all P〈0.05） in CKD3 group. Compared with the CKD2 group, IVSTd, 3D-LVMi increased and LVEDd, GCS decreased （all P〈0.05） in CKD3 group. Conclusion In the early stages of CKD, the left ventricular myocardial contractive function has reduced, which can be detected by 3D-STE with GCS.

关 键 词：肾疾病 超声心动描记术 三维 心室功能 左 

分 类 号：R692[医药卫生—泌尿科学] R540.45[医药卫生—外科学]