新生儿坏死性小肠结肠炎发病原因及预后研究进展  

Progress on pathogenesis and prognosis of neonatal necrotizing enterocolitis

作　　者：晏俪鸶 余加林[1] 

机构地区：[1]重庆医科大学附属儿童医院新生儿诊治中心,400014

出　　处：《国际儿科学杂志》2016年第6期470-473,共4页International Journal of Pediatrics

摘　　要：新生儿坏死性小肠结肠炎（neonatal necrotizing enterocolitis，NEe）是一种常见的胃肠道急症，属于新生儿期严重危及生命的疾病之一。其发病原因尚不完全明确，主要有早产、喂养不当、肠道感染和菌群失调、缺氧缺血及再灌注损伤等。疾病的临床分期、呼吸衰竭等严重并发症、治疗方法等多种因素均会影响NEC患儿的预后。该文就近期相关研究展开综述，为NEC的早期诊断、临床观察及治疗提供线索。Neonatal necrotizing enterocolitis （NEC）is a common gastrointestinal emergency, which belongs to one of the life-threatening diseases of neonatal infants. Its pathogenesises include premature birth,inappropriate feeding,intestinal infection and dysbacteriosis, hypoxic ischemic reperfusion injury, etc, which remain not fully known. The clinical stages, some severe complications such as respiratory failure and treatment etc, can affect the prognosis of neonatal infants with NEC. This article reviews the latest progress on related researches, which may provide clues to the early diagnosis, clinical observation and treatment of NEC.

关 键 词：新生儿坏死性小肠结肠炎 发病机制 预后 

分 类 号：R722.1[医药卫生—儿科]