红细胞分布宽度等相关指标水平对老年慢性心力衰竭患者预后的临床意义  

The significance of the level of the red cell distribution width and other related indicators to predict the prognosis in patients with chronic heart failure elderly

作　　者：董建新[1] 王宝芝[1] 

机构地区：[1]嘉应学院医学院附属医院心内科,广东省梅州514031

出　　处：《中国医师杂志》2016年第6期842-844,共3页Journal of Chinese Physician

基　　金：梅州市科技局立项课题（2013-B-32）

摘　　要：目的探讨红细胞分布宽度等相关指标水平对老年慢性心力衰竭患者预后的临床意义。方法回顾性分析住院死亡的86例老年慢性心力衰竭患者的临床资料（死亡组），并随机入选100例治疗好转的老年慢性心力衰竭患者为对照（对照组）。比较两组患者红细胞分布宽度（RDW）、超敏C-反应蛋白（hs-caP）、同型半胱氨酸（Hcy）、D-二聚体（DD）和氨基末端脑钠肽前体（NT—proB—NP）水平的差异。结果观察组RDW、hs—CRP、Hcy、DD和NT-proBNP水平高于对照组，差异有统计学意义（P〈0．01）。结论慢性心力衰竭是临床常见老年危重病，检测RDW、hs—CRP、Hcy、DD和NT-proBNP水平，对评估患者治疗效果、预测患者预后有着重要的临床意义。Objective To investigate the level of the red blood cell （RBC） distribution width and other related indicators to predict the prognosis in patients with chronic heart failure elderly. Methods Retrospective analysis was performed in the patients with chronic heart failure elderly which died in our hospital （ experimental group） and 100 patients were selected randomly that with heart failure elderly being im- proved by treatment （ control group）. The difference was compared in the level of the RBC distribution width （RDW）, high-sensitivity C-reactive protein （hs-CRP）, homocysteine （Hey）, D-dimer （DD）, and amino-terminal pro-brain natriuretic peptide （NT-proBNP） in two groups. Results The level of RDW, hs- CRP, Hey, DD, and NT-proBNP in experimental group were significantly higher than that in control group （ P 〈 0. 01 ）. Conclusions Chronic heart failure was common clinical critically ill in the elderly. There were important clinical significance and important predictors to detect the levels of RDW, hs-CRP, Hey, DD, and NT-proBNP in predicting prognosis and evaluating the effect of treatment.

关 键 词：红细胞 心力衰竭/代谢 C反应蛋白质/代谢 高半胱氨酸/代谢 纤维蛋白纤维蛋 白原降解物/代谢 利钠肽 脑/代谢 预后 

分 类 号：R541.6[医药卫生—心血管疾病]