苹果树枝的化学成分研究  

Chemical constituents isolated from branches of Malus pumila

作　　者：魏小聪 赵艳敏[1] 宋光明[1] 宋晓凯[2] 刘岱琳[1] 

机构地区：[1]中国人民武装警察部队后勤学院,天津300309 [2]中国矿业大学,江苏徐州221116

出　　处：《中草药》2016年第11期1845-1849,共5页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(31201345);天津市自然科学基金资助项目(13JCYBJC24400);中国博士后科学基金项目(2014M562674)

摘　　要：目的研究苹果Malus pumila树枝的化学成分。方法采用硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱以及HPLC等方法进行分离纯化,根据其理化性质和波谱数据鉴定化合物结构。结果从苹果树枝乙醇提取物的醋酸乙酯部位分离纯化得到11个化合物,分别鉴定为根皮素(1)、erlodictyol(2)、8-甲氧基山柰酚-7-O-鼠李糖苷(3)、槲皮素(4)、6-甲氧基槲皮素(5)、对原儿茶酸甲酯(6)、槲皮素-3-O-呋喃阿拉伯糖苷(7)、根皮苷(8)、金鱼草素-6-O-β-D-葡萄糖苷(9)、槲皮素-3-O-D-木糖(10)、3,4-二羟基苯甲酸乙酯(11)。结论化合物2和9为首次从蔷薇科植物中分离得到,化合物11为首次从该属植物中分离得到,化合物3为首次从该植物中分离得到。Objective To study the chemical constituents from the branches of Malus pumila.Methods Compounds were isolated and purified on many kinds of column chromatography,such as silica gel,Sephadex LH-20,ODS,and PHPLC.The structures of the obtained compounds were identified by their physical properties and spectroscopic data.Results Eleven compounds were separated and purified from the ethyl acetate extract from the branches of M.pumila.They were identified to be phloretin（1）,erlodictyol（2）,8-methoxyl-kaempferol-7-O-rhamnoside（3）,quercetin（4）,6-methoxy-quercetin（5）,protocatechuic acid methyl ester（6）,quercetin-3-O-arabinofuranosidase（7）,phlorizin（8）,aureusidin-6-O-β-D-glucoside（9）,quercetin-3-O-D-xylose（10）,and 3,4-dihydroxybenzoic acid ethyl ester（11）.Conclusion Compounds 2 and 9 are firstly reported from the plants of Rosaceae.Compound 11 is isolated from this genus and compound 3 is obtained from this plant for the first time.

关 键 词：苹果树枝 黄酮 8-甲氧基山柰酚-7-O-鼠李糖苷 金鱼草素-6-O-β-D-葡萄糖苷 3 4-二羟基苯甲酸乙酯 

分 类 号：R284.1[医药卫生—中药学]