新型铈苦味酸配合物表现和白蛋白的相互作用分析  

Analysis on Performance of a Novel Cerium Picorate Complex and Its Interaction With Albumin

作　　者：李春玲[1] 梁明慧[1] 王娜[1] 仇晓阳[2] 

机构地区：[1]商丘医学高等专科学校公共学科部化学教研室,河南商丘476000 [2]商丘师范学院化学化工学院,河南商丘476000

出　　处：《当代化工》2016年第6期1156-1158,1162,共4页Contemporary Chemical Industry

基　　金：商丘市科技公关项目;项目号:141055

摘　　要：分析了新型铈苦味酸配合物表现和白蛋白的相互作用分析。采用元素分析、红外光谱法、荧光光谱法、三维荧光光谱法、同步荧光光谱等,以分析配合物构成物质。结果表明配合物对3种白蛋白形成的荧光猝灭是静态猝灭,猝灭强弱依次如下:HAS(人血清白蛋白)>BSA(牛血清白蛋白)>VOA(鸡蛋清白蛋白)。通过计算分析了不同温度状态下配合物和3种白蛋白间结合的主要形式是依赖静电作用力。Performance of a novel cerium picorate complex and its interaction with albumin were analyzed. Structure and composition of the complex were investigated by elemental analysis, infrared spectroscopy, fluorescence spectrometry, 3D fluorescence spectroscopy, synchronous fluorescence spectroscopy and other research methods. The results show that fluorescence quenching of three kinds of albumin by the complex is static quenching, quenching intensity in turn is as follows： HAS （human serum albumin） 〉 BSA （bovine serum albumin） 〉 VOA （egg white protein）. The main form of combination between three kinds of albumin with the complex is dependent on the electrostatic force.

关 键 词：稀土配合物 荧光猝灭 白蛋白 

分 类 号：TQ028[化学工程]