宫颈环形电切术与子宫切除术间隔时间对术后并发症影响研究  

Effects of different time intervals between loop electrosurgical excision procedure and hysterectomy on postoperative complications

作　　者：孟亚萍[1,2] 陆琦[1] 王玉东[1] 

机构地区：[1]上海交通大学医学院附属国际和平妇幼保健院,上海200030 [2]上海市嘉定区中心医院,上海201800

出　　处：《中国实用妇科与产科杂志》2016年第7期689-692,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：上海交通大学"新百人计划"研究项目(XBR2013097);上海市卫生局"妇科常见病和多发病"的重点项目(20124027)

摘　　要：目的探讨宫颈环形电切术（LEEP）与（广泛）子宫切除术的时间间隔对术后并发症的影响。方法回顾性分析上海交通大学附属国际和平妇幼保健院2008年1月至2014年7月接受LEEP术后再行（广泛）子宫切除术的478例患者临床资料，按照LEEP与（广泛）子宫切除术时间间隔分为2组：A组O～2周（n=118），B组〉2周（n=360）。比较两组患者术中出血量、住院时间、术后并发症的发生情况及其与时间间隔的相关性。结果A组术中出血量较B组增多，住院时间明显延长（P〈0．05），两组术后发热、尿路感染等并发症发生率比较差异均无统计学意义（P〉0．05）。按照手术方式、手术范围分层分析显示，两组术中出血量、术后发热、住院时间比较，差异均无统计学意义（P〉0．05）。多因素非条件kgistic回归分析显示，伤口感染是术后发热的独立危险因素（P〈0．05），LEEP术和（广泛）子宫切除术的时间间隔与术后发热无显著相关性（P〉0．05）。结论LEEP术和（广泛）子宫切除术的时间间隔与术后并发症发生率无相关性，临床上可根据患者的病情及需求选择广泛性子宫切除术的最佳手术时机。Objective To investigate the influences of different time intervals between loop electrosurgical excision pro- cedure （LEEP） and （radical） hysterectomy on postoperative complications. Methods Totally 478 patients who re- ceived subsequent hysterectomy or radical hysterectomy after LEEP in International Peace Maternity and Child Health Hospital affiliated to Shanghai Jiao Tong University between Jan.2008 and July 2014 were included and retrospectively analyzed. The patients were divided into two groups according to the time interval between LEEP and （radical） hysterec- tomy, Group A （within 2 weeks, n= 118 ） and Group B （〉 2 weeks, n=360）. The volume of intraoperative blood loss, hos- pital stay and postoperative complications and their correlation with the time interval between two groups were compared. Results The intraoperative blood loss and hospital stay in Group A was significantly-increased than that in Group B （P〈O.05）, and there was no siguificance on the incidence of postoperative febrile and urinary tract infection between two groups （P〉0.05）.Stratified by the scope and type of operation, the intraoperative blood loss and postoperative febrile in two groups were not statistically different （P〉O.05）. Multivariate logistic regression analysis showed that wound infection was independent risk factor for postoperative febrile, and time intervals between LEEP and （radical） hysterectomy was not correlated with postoperative febrile （P〉0.05）.Conclusion The time intervals between LEEP and （radical） hysterectomy is not correlated with postoperative complications, and the hysterectomy may be performed at the best operation opportunity according to patients ＇ condition and demand.

关 键 词：环形电切术 子宫切除术 广泛性子宫切除术 时间间隔 并发症 

分 类 号：R713.42[医药卫生—妇产科学]