高血压病患者脉压与冠心病危险性的相关性研究  

Correlation between pulse pressure and risk of coronary artery disease in patients with hypertension

作　　者：郭武松 刘亚辉[1] 邓庆才[1] 

机构地区：[1]四川省资中县人民医院,四川内江641200

出　　处：《心血管病防治知识（学术版）》2016年第5期9-11,共3页Prevention and Treatment of Cardiovascular Disease

摘　　要：目的探讨高血压病患者脉压与冠心病危险性的相关性。方法本研究选取了2012年4月至2013年4月我院收治的35例高血压并冠心病患者(冠心病组)及35例高血压患者(非冠心病组)作为研究对象,采用Logistic回归分析法分析脉压与冠心病危险性的相关性。结果收缩压、脉压、年龄与冠心病的发病呈正相关,舒张压与冠心病的发病呈负相关。收缩压每增加5mm Hg,患者发生冠心病的风险增加1.61倍;脉压每增加5mm Hg,患者发生冠心病的风险增加4.26倍;年龄每增加10岁,患者发生冠心病的风险增加1.09倍;舒张压每增加5mm Hg,患者发生冠心病的风险降低1.04倍。脉压与冠心病患者的危险性关系最大。结论在高血压病患者中,脉压是冠心病发病的重要危险因素。Objective To investigate the correlation between pulse pressure and the risk of coronary artery disease（CHD） in patients with hypertension. Methods A total of 35 hypertensive patients with CHD（CHD group） and35 hypertensive patients without CHD（non-CHD group） who were admitted to our hospital from April 2012 to April2013 were enrolled as subjects. Logistic regression analysis was performed to investigate the correlation between pulse pressure and CHD risk. Results Systolic blood pressure, pulse pressure, and age were positively correlated with the risk of CHD, while diastolic blood pressure was negatively correlated with the risk of CHD. A 5-mm Hg increment in systolic blood pressure was associated with a 1.61-fold increase in CAD risk, a 5-mm Hg increment in pulse pressure was associated with a 4.26-fold increase in CAD risk, a 10-year increment in age was associated with a 1.09-fold increase in CAD risk, and a 5-mm Hg increment in diastolic blood pressure was associated with a 1.04-fold reduction in CAD risk.Pulse pressure was the most important influential factor for CHD. Conclusion Pulse pressure is an important influential factor for CHD in hypertensive patients.

关 键 词：高血压 脉压 冠心病 危险性 研究 

分 类 号：R544.1[医药卫生—心血管疾病]