Characterization of a recombinant Akabane mutant virus with knockout of a nonstructural protein NSs in a pregnant goat model  

作　　者：Akiko Takenaka-Uema Norasuthi Bangphoomi Chieko Shioda Kazuyuki Uchida Fumihiro Gen Kentaro Kato Takeshi Haga Shin Murakami Hiroomi Akashi Taisuke Hoimoto 

机构地区：[1]Department of Veterinary Microbiology,Graduate School of Agricultural and Life Sciences,The University of Tokyo [2]Department of Infection Control and Disease Prevention,Graduate School of Agricultural and Life Sciences,The University of Tokyo [3]Department of Preclinical and Applied Animal Science,Faculty of Veterinary Science,Mahidol University [4]Department of Veterinary Pathology,Graduate School of Agricultural and Life Sciences,The University of Tokyo [5]National Research Center for Protozoan Diseases,Obihiro University of Agriculture and Veterinary Medicine

出　　处：《Virologica Sinica》2016年第3期274-277,共4页中国病毒学（英文版）

基　　金：supported in part by a Research and Development Project for Application in Promoting New Policies in Agriculture,Forestry and Fisheries grant from the Ministry of Agriculture, Forestry and Fisheries;a Grant-in-Aid from the Ministry of Education,Culture,Sports,Science and Technology of Japan

摘　　要：Dear Editor,Akabane virus(AKAV),an orthobunyavirus,is transmitted primarily by biting midges and is widely distributed throughout the world except the Europe.AKAV was first isolated from mosquitoes in Japan(Oya et al.,1961).Although pregnant cows,ewes,and goats infected with AKAV exhibit no clinical signs of disease,in utero infections result in abortion,premature birth,stillbirth。Dear Editor,Akabane virus（AKAV）,an orthobunyavirus,is transmitted primarily by biting midges and is widely distributed throughout the world except the Europe.AKAV was first isolated from mosquitoes in Japan（Oya et al.,1961）.Although pregnant cows,ewes,and goats infected with AKAV exhibit no clinical signs of disease,in utero infections result in abortion,premature birth,stillbirth,

关 键 词：pregnant mutant abortion premature birth primarily vaccine throughout removed inoculated 

分 类 号：S852.65[农业科学—基础兽医学]