外周血白细胞与缺血性卒中  

Peripheral blood leukocytes and ischemic stroke

作　　者：崔宁[1] 刘丽[2] 

机构地区：[1]内蒙古医科大学研究生学院,呼和浩特010059 [2]赤峰市医院神经内科,024000

出　　处：《国际脑血管病杂志》2016年第5期459-462,共4页International Journal of Cerebrovascular Diseases

摘　　要：动脉粥样硬化是缺血性卒中的病理学基础，外周血白细胞参与动脉粥样硬化的发生和进展过程，并造成血管内皮损伤。急性缺血性卒中后外周免疫细胞发生一系列变化，引起炎性细胞向脑组织浸润。白细胞计数增高与冠状动脉粥样硬化性心脏病的发生和预后密切相关。也有研究显示，外周血白细胞计数增高可能会影响缺血性卒中的发生、神经功能缺损、复发和死亡。文章对外周血白细胞与缺血性卒中的关系进行了综述。Atherosclerosis is the pathological basis of ischemic stroke. Peripheral blood leukocytes are involved in the occurrence and progression of atherosclerosis and cause vascular endothelial injury. A series of changes of peripheral immune cel take place after acute ischemic stroke and cause inflammatory cel infiltrating into the brain tissue. The elevated leukocyte count is closely associated with the occurrence and prognosis of coronary atherosclerotic heart disease. Studies have also shown that the elevated leukocyte count may influence the occurrence of ischemic stroke, neurological deficit, recurrence, and death. This article reviews the relationship between peripheral blood leukocytes and ischemic stroke.

关 键 词：卒中 脑缺血 炎症 白细胞 白细胞计数 中性白细胞 炎症介导素类 

分 类 号：R743.3[医药卫生—神经病学与精神病学]