肥胖、体脂率、血脂水平异常与糖尿病前期的关系探讨  

Association of obesity,body fat percentage,and abnormal blood lipid level with prediabetes

作　　者：黄晶晶[1] 尹莲花[1] 许艺惠[1] 黄守清[1] 

机构地区：[1]福建中医药大学附属第二人民医院,福建福州350003

出　　处：《湖南中医杂志》2016年第6期4-6,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：福建中医药大学重点学科专项校管课题资助(编号:X2014043-学科)

摘　　要：目的:探讨肥胖、体脂率、血脂异常与糖尿病前期的关系。方法:采用病例对照研究方法,选取福建省第二人民医院健康管理中心的体检者214例作为研究对象,其中糖尿病前期(观察组)108例,正常对照组106例,对研究对象进行体格检查、体脂率检测和生化指标等实验室检测。结果:观察组体质量(BW)、体质量指数(BMI)、瘦体质量(FFM)、体脂率(BF%)、三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)均高于对照组,差异有统计学意义(P<0.05或P<0.01);观察组超重及肥胖检出率为68.5%、高胆固醇检出率为37.0%、高三酰甘油检出率为38.9%、体脂异常检出率为38.9%,均高于对照组的37.7%、16.9%、16.9%、22.6%,差异有统计学意义(P<0.01);经多因素非条件Logistic回归分析显示高胆固醇、高三酰甘油和肥胖为糖尿病前期发病的危险因素。结论:肥胖、血脂异常与糖尿病前期相关,控制体质量、合理膳食是预防糖尿病前期发生的重要措施。Objective： To investigate the association of obesity,body fat percentage,and abnormal blood lipid level with prediabetes. Methods： A case- control study was performed for 214 persons who underwent physical examination in Health Management Center of The Second People＇s Hospital of Fujian. Among these patients,108 had prediabetes（ observation group） and 106 were enrolled in the normal control group. All the study subjects underwent physical examination,measurement of body lipid percentage,and laboratory tests for the measurement of biochemical parameters. Results： Compared with the normal control group,the observation group had significantly higher body weight,body mass index,fat- free mass,body fat percentage,triglyceride（ TG）,total cholesterol,and low- density lipoprotein（ P〈0. 05 or P〈0. 01）. The observation group also had significantly higher detection rates of overweight / obesity,high cholesterol,high TG,and abnormal body fat than the control group（ 68. 5% /37. 0% /38. 9% /38. 9% vs37. 7% /16. 9% /16. 9% /22. 6%,P〈0. 01）. The multivariate non- conditional logistic regression analysis showed that high cholesterol, high TG, and obesity were risk factors for the development of prediabetes. Conclusion： Obesity and abnormal blood lipid level are associated with prediabetes,and the control of body weight and a proper diet are important methods to prevent prediabetes.

关 键 词：糖尿病前期 体脂率 肥胖 血脂异常 

分 类 号：R259.871[医药卫生—中西医结合]