恶性肿瘤患者多重耐药菌医院感染监测与干预效果  

Study on the monitoring and intervention effect of multidrug-resistant organism infections in a tumour hospital

作　　者：龚光明[1] 李桃[1] 徐俊炜[1] 

机构地区：[1]江苏省南通市肿瘤医院,江苏南通226361

出　　处：《中国消毒学杂志》2016年第6期576-578,共3页Chinese Journal of Disinfection

基　　金：江苏省南通市科技计划项目(HS2012062)

摘　　要：目的研究住院恶性肿瘤患者多重耐药菌(MDROs)医院感染及其干预效果。方法通过目标性监测方法,对某医院恶性肿瘤住院患者MDROs医院感染进行调查,分析感染危险因素,实施综合干预措施。结果该医院2年间收治恶性肿瘤住院患者55 336例,发生MDROs感染患者69例,感染率为0.12%。实施目标性监测的2014年度MDROs感染率明显低于2013年,呈下降趋势。从69例MDROs感染患者送检标本中分离出的病原菌主要是大肠埃希菌和葡萄球菌属,构成比分别为53.62%和30.44%。病原菌主要分离自血液,占27.54%;其次为痰液和引流液,分别占23.19%和18.84%。MDROs感染部位以手术部位、血液和呼吸道感染为主,构成比分别占26.09%、23.19%和20.29%。结论恶性肿瘤患者MDROs感染主要发生在手术部位、血液和呼吸道,病原菌以大肠埃希菌和葡萄球菌属为主,应结合此特点有针对性地加强预防和控制。Objective To study the intervention measures of multidrug- resistant organism（MDROs） infection in patients with malignant tumour.Methods The targeted monitoring was used for the hospitalized tumor patients with MDROs infections to analyze the risk factors of infection,and to implement comprehensive intervention measures.Resules During these two years,55 336 cancer patients were admitted in this hospital and 69（0.12%） cases of MDROs infection developed.The infection rates of MDROs in 2014 which was targetedlg monitored was significantly lower than that of 2013,with a downward trend.strains of Escherichia coli was given priority to the pathogenic bacteria of MDROs nosocomial infection with the detection rate of 53.62%,then followed by Staphylococcus with the detection rate of 30.44%.The MDROs infection specimens were mainly isolated from the blood that accounted for 27.54%; then followed by sputum and drainage fluid,accounted for 23.19%,18.84% respectively.The highest constituent ratio of MDROs infection was operation site that accounted for 26.09%,then followed by blood system and respiratory tract infection that accounted for 23.19%,20.29% respectively.Conclusion The MDROs infections of malignant tumor patients mainly occur in the surgical site infection,blood system and respiratory tract infection,and pathogenic bacteria is given priority to E.coli and Staphylococcus aureus.We should strengthen prevention and control measures combined with the characteristics.

关 键 词：恶性肿瘤 多药耐药菌 医院感染 目标性监测 干预措施 

分 类 号：R378[医药卫生—病原生物学]