儿童腺样体肥大菌群分布Meta分析  

Meta analysis of adenoid bacterial distribution in children with adenoid hypertrophy

作　　者：韩书婧[1] 张亚梅[2] 鲁洁[1] 初平 刘悄吟[2] 金雅琼[1] 于永波[1] 吴云肖[1] 郭永丽[1] 邰隽[2] 倪鑫[1,2] 

机构地区：[1]首都医科大学附属北京儿童医院,北京市儿科研究所,儿童耳鼻咽喉头颈外科疾病北京市重点实验室,北京100045 [2]首都医科大学附属北京儿童医院耳鼻咽喉头颈外科,北京100045

出　　处：《中国耳鼻咽喉头颈外科》2016年第6期313-317,共5页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：北京市科技计划(Z131100006813044);首都卫生发展科研专项(2014-1-2091)联合资助

摘　　要：目的明确儿童腺样体肥大的菌群分布情况。方法英文文献通过对Pub Med、Embash和Medline数据库,中文文献通过对中国期刊全文数据库（CNKI）、中国科技期刊全文数据库（VIP）、万方数据库进行系统检索,收集各数据库自建库到2015年7月发表的所有儿童腺样体肥大细菌分布情况研究的文献。检索条件：英文检索词包括＂adenoid＂、＂microbiology＂、＂bacteria＂;中文检索词包括＂腺样体＂、＂细菌＂和＂菌群＂。结果纳入研究的9篇文献共计1162份腺样体标本,流感嗜血杆菌检出率为0.21（95%CI,0.09~0.32）,金黄色葡萄球菌检出率为0.14（95%CI,0.09~0.20）,肺炎链球菌检出率为0.15（95%CI,0.08~0.22）。结论流感嗜血杆菌、金黄色葡萄球菌和肺炎链球菌是儿童腺样体肥大的菌群分布中3种主要的致病菌,为指导儿童腺样体肥大的诊疗提供了依据。OBJECTIVE To illuminate the adenoid bacteria distribution in children with adenoid hypertrophy.METHODS PubMed,Embash,Medline,CNKI,VIP Information and Wanfang data were searched for studies on the adenoid bacteria distribution and adenoid hypertrophy.Random effects meta-analysis was used to pool data.RESULTS Nine studies were included in this meta analysis.The pooled detection rates of haemophilus influenza,staphylococcus aureus and streptococcus pneumonia were 0.21（95%CI,0.09-0.32）,0.14（95%CI,0.09-0.20） and 0.15（95%CI,0.08-0.22） respectively.CONCLUSION Haemophilus influenzae,staphylococcus aureus,and streptococcus pneumoniae are three main kinds of pathogenic bacteria of adenoid hypertrophy in children.

关 键 词：儿童 Meta分析[文献类型] 菌群 腺样体肥大 

分 类 号：R766[医药卫生—耳鼻咽喉科]