轻度创伤性脑损伤评估及管理的研究进展  

Advances in research of the evaluation and management of mild traumatic brain injury

作　　者：何磊磊[1] 丁礼[1] 陆士奇[1] 李军根[1] 王亮[1] 郭艳霞[1] 肖接承[1] 

机构地区：[1]苏州大学附属第一医院急诊外科,苏州215006

出　　处：《中华急诊医学杂志》2016年第7期959-964,共6页Chinese Journal of Emergency Medicine

摘　　要：依据GCS（Glasgowcomascale）评分，创伤性脑损伤（traumaticbraininjury，TBI）可分三度，即轻度、中度、重度，其中轻度创伤性脑损伤（mildtraumaticbraininjury，mTBI）约占总TBI的90％，且其发病率有逐年升高趋势，已成为一个严重的社会公共卫生问题。目前对mTBI缺乏统一的定义，临床上认为mTBI和脑震荡是可以互换的术语。近年来，随着脑成像、生物标志物和神经病理学的研究不断进展，mTBI相关的知识不断修改、更新。鉴于mTBI在急诊和社区发病率高，而关于mTBI长期影响的研究数据又相对缺乏，因此如何减少mTBI的发病率和成本、减轻延迟性损伤，以及采取怎样的干预措施可减轻长期后遗症，仍需进一步研究。Traumatic brain injury （TBI） has been classified as mild, moderate, or severe, on the basis of the Glasgow coma scale （GCS） score. Mild TBI is estimated to account for 90% of all eases of TBI, and it has become a serious public health problem, with morbidity increasing year by year. At present, there is a lack of accepted uniform definition of mild TBI. Clinically, mild TBI and concussion are interchangeable terms. In recent years, advances in brain imaging, biomarkers determination, and neuropathology have encouraged people to revise and update their knowledge about mild TBI. In view of the high prevalence of mild TBI in the emergency and community, and the absence of the data concerning the long-term effects of mild TBI, further research is needed about how to reduce morbidity and costs, alleviate delayed consequences, and develop evidence-based interventions to improve outcomes.

关 键 词：轻度创伤性脑损伤 GCS评分 脑震荡 临床管理 脑震荡后综合征 预后 

分 类 号：R651.15[医药卫生—外科学]