芪芍活血颗粒的醇提工艺优选  

Optimization of Ethanol Extraction Process for Qishao Huoxue Granules(芪芍活血颗粒)

作　　者：杜天信[1,2] 郑超[2] 杜志谦[1,2] 夏华玲 马守芳 

机构地区：[1]河南省正骨研究院,河南洛阳471002 [2]河南中医学院,河南郑州450008

出　　处：《中医药导报》2016年第14期61-63,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：河南中医学院2014年度研究生创新培养基地立项项目(2014YCX029)

摘　　要：目的:优选芪芍活血颗粒的醇提工艺。方法:采用正交试验法,以芍药苷和干浸膏收率为评价指标,考察加醇量、醇浓度、提取时间和提取次数等4个因素对提取工艺的影响。结果:最佳提取工艺为12倍量醇,提取3次,每次1.5h;乙醇浓度为70%。结论:优选的工艺合理可行,提取效率高,适合工业生产。Objective： To optimize ethanol extraction technology for the Qishao Huoxue Granules （芪芍活血颗粒, QSHXG）. Methods： With the content of paeoniflorin and extract rate as indexes, effects of the amount of ethanol, the concentration, extraction time and extraction times were optimized by orthogonal test. Results： Optimum extraction process was as follows： extracted 3 times with 12-fold 70% ethanol, 1.5 hours each time. Conclusion： The optimized process is reasonable and feasible, and it can provide reference for the industrialized production.

关 键 词：芪芍活血颗粒 醇提工艺 正交试验 芍药苷 

分 类 号：R284.2[医药卫生—中药学]