短期应用草酸艾司西酞普兰对心肌梗死冠状动脉支架植入术后焦虑的疗效观察  

The Effect of Short-term Application of Escitalopram on Anxiety of Myocardial Infarction Patients Undergoing Coronary Stent Implantation

作　　者：董惠洁[1] 季晓飞[2] 

机构地区：[1]大连医科大学附属第二医院心内科,辽宁大连116023 [2]大连医科大学附属第一医院神经内科,辽宁大连116011

出　　处：《医学与哲学（B）》2016年第6期74-76,F0003,共4页Medicine & Philosophy(B)

摘　　要：为缓解冠状动脉支架植入术患者继发焦虑及评估抗焦虑药物应用时程,本研究对160例冠状动脉支架术后继发焦虑患者随机分为两组,研究组加用草酸艾司西酞普兰治疗10周,采用汉密尔顿焦虑量表及心肌梗死后生活质量问卷对两组患者随访12个月,发现草酸艾司西酞普兰短期治疗可显著减少患者的焦虑评分(P<0.05);且患者6个月内生活质量明显提高;同时,仅有11例患者在草酸艾司西酞普兰停药12个月内再发焦虑,且焦虑评分与治疗前无差异(P>0.05)。因此短期应用草酸艾司西酞普兰可有效改善冠状动脉支架术后患者的焦虑症状及生活质量。In order to effectively alleviate secondary anxiety and evaluate the application of anti-anxiety drugs of myocardial infarction patients undergoing coronary stent implantation,160 patients with secondary anxiety were randomly divided into two groups in 2 weeks after coronary stent implantation.The study group patients were treated with 10 weeks escitalopram on the basis of conventional therapy on coronary heart disease.Hamilton Anxiety scale and the quality of life questionnaire after myocardial infarction were used in two groups of patients for 12 months.Results showed that compared to the conventional treatment group,escitalopram short-term treatment can significantly reduce anxiety symptoms and Hamilton Anxiety Rating in patients within 10weeks（P〈0.05）;and the quality of life of the patients with escitalopram treatment was significantly higher than that in the conventional treatment group.There were only 11 cases with short-term escitalopram treatment recurrent anxiety symptoms within 12 months,and there was no significant increase in anxiety score before treatment（P〉0.05）.Therefore,for the coronary stent implantation patients with secondary anxiety,shortterm application of escitalopram can effectively improve anxiety symptoms and postoperative quality of life.

关 键 词：草酸艾司西酞普兰 冠状动脉支架植入术 焦虑 心肌梗死后生活质量问卷 

分 类 号：R541.4[医药卫生—心血管疾病] R749.92[医药卫生—内科学]