丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用  

The Effects of Continuous Infusion of Propofol and Etomidate Mixture in Painless Gastroscopy Anesthesia

作　　者：付山[1] 袁磊[1] 张宇峰[1] 杨建志[1] 吴斌斌[1] 

机构地区：[1]汉中市中心医院手术麻醉科,陕西汉中723000

出　　处：《现代生物医学进展》2016年第22期4325-4328,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用效果。方法:2013年9月到2015年2月选择在我院进行无痛胃肠镜检查患者120例,根据随机数字表法分为治疗组60例与对照组60例,对照组给予丙泊酚辅助持续泵注麻醉,治疗组给予丙泊酚和依托咪酯混合液辅助持续泵注麻醉。结果:所有患者都完成检查,两组MAP与HR值在给药后2 min与给药前比较差异都有统计学意义(P<0.05),在组间相比较无显著性差异(P>0.05),其余时间点的上述值在组内与组间比较均无显著性差异(P>0.05)。治疗组的诱导时间与离院时间都明显少于对照组(P<0.05),对比两组的检查时间及苏醒时间,无显著性差异(P>0.05)。治疗组检查后1天内出现的恶心、呕吐、头晕等并发症发生情况明显少于对照组(P<0.05)。结论:丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用对于患者的血流动力学影响小,能促进麻醉效果的提高,减少不良反应的发生,值得推广应用。Objective： To investigate the effects of continuous Infusion ofpropofol and etomidate mixture in painless gastroscopy anesthesia. Methods： 120 patients who were treated with painless, selected gastrointestinal endoscopy were collected From September 2012 to February 2015 in our hospital and were equally divided into the treatment group of 60 patients and the control group of 60 patients. The patients in control group were received propofol auxiliary continuous infusion anesthesia, and the patients of the treatment group were received propofol and etomidate mixture assisted continuous infusion anesthesia. Results： All patients were completed the examination, The MAP and HR values at 2 rain after the administration in two groups compared with before administration were statistically significant differences （P 〈0.05）, but no difference was detectable between two groups. The above values for the remaining time in the group and between the two groups showed no significant difference （P〉 0.05）. The induction time and time away from the hospital in the treatment group were significantly less than that of the control group （P 〈0.05）, while the examination time and wake time were no statistically significant between two groups （P〉 0.05）. After treatment, the nausea, vomiting, dizziness, skin itching and other complications in the treatment group were significantly less than those of the control group （P 〈0.05）. Conclusions： Continuous infusion anesthesia of propofol and etomidate mixture in painless gastroscopy has less hemodynamic effect, and it can promote the effect of anesthesia and reduce the incidence of adverse reactions, worthy of promotion and applications in clinic.

关 键 词：丙泊酚 依托咪酯 无痛胃肠镜 麻醉 

分 类 号：R614[医药卫生—麻醉学]