佳木斯市2014年健康儿童脊髓灰质炎中和抗体监测  

Surveillance on poliomyelitis Antibody level of healthy children in Jiamusi city in 2014

作　　者：宋婧[1] 宋长江[1] 吕珀[1] 王晗[1] 王晓宇[1] 马玉杰[1] 

机构地区：[1]黑龙江省疾病预防控制中心,黑龙江哈尔滨150030

出　　处：《中国公共卫生管理》2016年第3期381-382,共2页Chinese Journal of Public Health Management

摘　　要：目的了解佳木斯市1~4岁健康人群脊髓灰质炎（脊灰）中和抗体水平。方法随机抽取1~,2~,3~,4~岁4个年龄组的健康儿童进行脊灰中和抗体监测,并且对部分儿童免前免后抗体水平进行比较。结果 305名健康儿童脊灰I、II、III型中和抗体阳性率分别为94.75%、95.41%、93.11%,GMT分别为1：67.89、1：65.77、1：55.21,同一型别抗体的GMT值在不同年龄间存在差异。116名健康儿童的脊灰抗体水平免疫后较免疫前有大幅提高。结论佳木斯市1~4岁儿童具有较高的疫苗免疫覆盖率,建立了稳固的免疫屏障。Objective To investigate the immunity levels of polio neutralized antibody of 1to 4years old children in Jiamusi city. Methods 305 healthy children who were divided into 4 groups of 1,2,3,4 years old, respectively. Compare some childrens＇ GMT before and after the vaccination. Results Rates of neutralized antibodies positive to I, II and III were94.75%, 95.41% and 93.11%, GMTs of neutralized antibodies for I, II and III were 1：67.89, 1：65.77 and 1：55.21,respectively. The result showed difference between the 4 groups for the same serotype.116 healthy children of polio immune antibody level after a has greatly increased in the past the immune. Conclusion Rates of neutralized antibodies of polio are generally high in investigated 1to 4years old children in Jiamusi. These had been formed firmly.

关 键 词：脊髓灰质炎 中和抗体 阳性率 几何平均滴度 

分 类 号：R183[医药卫生—流行病学] R117[医药卫生—公共卫生与预防医学]