瓜菜类病原细菌耐药外排泵RND研究进展  

Advances in RND-type multi-drug efflux pumps from cucurbit and vegetable pathogenic bacteria

作　　者：王真[1,2] 赵廷昌[2] 杨玉文[2] 关巍[2] 胡俊[1] 

机构地区：[1]内蒙古农业大学,呼和浩特010019 [2]中国农业科学院植物保护研究所.植物病虫害生物学国家重点实验室,北京100193

出　　处：《中国瓜菜》2016年第7期1-8,共8页China Cucurbits And Vegetables

基　　金：国家西甜瓜产业技术体系(CARS-26);中国农业科学院科技创新工程项目资助;北京市自然基金(6162023);公益性行业(农业)科研专项(201003066)

摘　　要：近年来,瓜菜类作物病原细菌的耐药性日益增强,增加了瓜菜相关病害防治的难度。存在于瓜菜作物病原细菌中的外排泵耐药结节分化家族(RND)与细菌的耐药性及细菌/植物互作关系密切。笔者根据有关文献综述了RND外排泵的结构与功能、细菌/植物互作过程中外排泵的作用以及外排泵抑制剂(EPIS)的相关研究进展,为瓜类和蔬菜类作物病原细菌耐药性的研究提供参考。In recent years, drug resistance of bacteria causing diseases on cucurbits and vegetables has been increasingly reported which caused huge difficluties in cucurbit and vegetable prevention. Resistance-nodulation-division family（RND） is one of the most important efflux pump family in cucurbit and vegetable pathogenic bacteria, which is closely related to bacteria multidrug resistance and interactions between pathogenic bacteria and plants. We describe structures and functions of RND efflux pumps, relationships between efflux pumps and bacterial/plant interactions as well as the relevant research of efflux pump inhibitors（EPIS）. This review will provide references for further studies on drug resistance of cucurbit and vegetable pathogenic bacteria.

关 键 词：葫芦科 蔬菜 病原细菌 耐药性外排泵 细菌/植物互作 外排泵抑制剂 

分 类 号：S432.42[农业科学—植物病理学]