基于中医传承辅助平台挖掘《临证指南医案》治疗泄泻方剂组方规律  

Analysis on regularity of prescriptions in "a guide to clinical practice with medical record" for diarrhoea based on traditional Chinese medicine inheritance support system

作　　者：何兰娟[1] 朱向东[1] 

机构地区：[1]甘肃中医药大学,甘肃兰州730000

出　　处：《中国中药杂志》2016年第12期2344-2349,共6页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81360541)

摘　　要：基于中医传承辅助平台(V2.5),分析叶氏《临证指南医案·泄泻》篇中治疗泄泻的组方用药规律,为进一步挖掘中医药治疗泄泻及新药法研发提供参考。应用中医传承辅助平台,构建中医药治疗泄泻的方剂数据库,采用软件集成的数据挖掘方法,对方剂数据库进行四气、五味、归经分布及频次统计、证型分布、组方规律、新方分析。通过对治疗泄泻的94首方剂分析,确定了处方中药物出现的频次、常用药对及组合,演化得到新处方13首。研究表明,《临证指南医案》中收录治疗泄泻的方剂以祛湿、补虚为主,药性多偏于温平,药味苦甘辛,体现了"运脾化湿"的治疗原则。To analyze the regularities of prescriptions in ＂ a guide to clinical practice with medical record＂（ Ye Tianshi） for diarrhoea based on traditional Chinese medicine inheritance support system（ V2. 5）,and provide a reference for further research and development of new traditional Chinese medicines in treating diarrhoea. Traditional Chinese medicine inheritance support system was used to build a prescription database of Chinese medicines for diarrhoea. The software integration data mining method was used to analyze the prescriptions according to ＂ four natures＂, ＂ five flavors＂ and ＂ meridians＂ in the database and achieve frequency statistics,syndrome distribution,prescription regularity and new prescription analysis. An analysis on 94 prescriptions for diarrhoea was used to determine the frequencies of medicines in prescriptions,commonly used medicine pairs and combinations,and achieve 13 new prescriptions. This study indicated that the prescriptions for diarrhoea in ＂ a guide to clinical practice with medical record＂ are mostly of eliminating dampness and tonifying deficienccy,with neutral drug property,sweet,bitter or hot in flavor,and reflecting the treatment principle of ＂ activating spleen-energy and resolving dampness＂.

关 键 词：泄泻 中医传承辅助平台 方剂 组方规律 

分 类 号：R289.5[医药卫生—方剂学]