不同活血化瘀中药注射液对急性脑梗死的疗效及成本-效果分析  

Therapeutic Effect of Different Traditional Chinese Medicine Injection to Acute Cerebral Infarction and Cost- Eeffectiveness Analysis

作　　者：赖珺[1] 李丹[1] 巫莉萍[1] 薛小燕[1] 张四青[1] 

机构地区：[1]赣州市人民医院,江西赣州341000

出　　处：《江西中医药大学学报》2016年第3期36-39,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：赣州市卫生局项目(赣卫科教字[2014]201407)

摘　　要：目的:结合药物经济学、血流变学方法、凝血功能和药物不良反应的监测,对2种活血化瘀中药注射液治疗急性脑梗死的疗效进行比较研究。方法:选取2013年1月-2014年12月60例急性脑梗死患者,分为丹红组和疏血通组,14天为1个疗程,观察疗效并进行成本-效果分析,观察2组治疗方案对患者血流变学、凝血功能的影响及不良反应的发生情况。结果:丹红组与疏血通组的成本分别为2613.52、1680.00元,总有效率分别为80.00%、90.00%,增量成本-效果分别为32.67%、18.67%,其中疏血通组与丹红组比较,总有效率较高且具有显著性差异(P<0.05),增量成本-效果较低。2组治疗后血流变学和凝血功能各项指标与治疗前比较均有显著性差异(P<0.05)。治疗后,疏血通组与丹红组比较,对血流变学指标的改善较明显,对凝血功能指标的改善也较明显且具有显著性差异(P<0.05)。2组均未发生不良反应。结论:疏血通组较丹红组为更有效、经济的方案,且安全性好,值得在临床上推广。Objective： To study the curative effect of 2 traditional Chinese medicine injections on acute cerebral infarction with cost- effectiveness analysis. Monitor blood rheology,coagulation function and drug adverse effect. Methods： A total of 60 patients with acute cerebral infarction were divided into 2 groups according to different therapeutic regimens,Shuxuetong and Danhong injection groups. 14 days was taken as a course. The curative effect,blood rheology and coagulation function were monitored and analyzed cost- effectiveness by pharmaco- economic methods. Observe drug adverse effect of 2 traditional Chinese medicine injections. Results： Cost for Danhong injection was 2613. 52 yuan with effectiveness ratio of 80. 00% and the incremental cost- effectiveness was 32. 67%. Meanwhile cost for Shuxuetong injection was 1680 yuan with effectiveness ratio of 90. 00% which was higher than Danhong injection. And the incremental cost- effectiveness was 18. 67% which was lower than Danhong injection. After one course,the indexes of blood rheology and coagulation function of both groups were significantly improved compared with before. Meanwhile Shuxuetong injection improved the indexes of blood rheology and coagulation function more obviously than Danhong injection,and the difference of indexes of coagulation function were statistically significant. There was no drug adverse effect happened in the course of both group. Conclusion： Shuxuetong injection is preferable therapeutic regimen and it is safe and worthy of promotion in clinical practice.

关 键 词：中药注射液 急性脑梗死 成本-效果分析 

分 类 号：R277.7[医药卫生—中医学]