溶剂萃取-GC-MS/MS测定水中邻苯二甲酸二(2-乙基己基)酯  

Determination of di-(2-ethylhexyl) phthalate in water by solvent extraction and gas chromatography-tandem mass spectrometry

作　　者：杜利敏[1] 王彦平[2] 路守栋[1] 张瑞[1] 王龑[1] 

机构地区：[1]郑州市疾病预防控制中心,河南郑州450007 [2]河南农业职业学院,河南郑州451450

出　　处：《现代预防医学》2016年第13期2432-2434,2441,共4页Modern Preventive Medicine

摘　　要：目的建立简便快速检测生活饮用水及水源水中邻苯二甲酸二（2-乙基己基）酯（DEHP）的GC-MS/MS测定方法。方法取100.0 m L水,加入2.00 m L正己烷,充分振荡提取,静置分层后,取正己烷层1.00μL于GC-MS/MS定性定量测定。结果该方法的检出限为0.000 02 mg/L,相对标准偏差〈3%,回收率在85.0%~103.3%之间。结论该方法简便快速、准确可靠,适合于水样中DEHP的定量测定。Objective To establish a rapid and accurate method for determination of di-（ 2- ethylhexyl） phthalate（ DEHP） in drinking water and source water by solvent extraction coupled with gas chromatography- tandem mass spectrometry（ GC- MS /MS） in multiple reaction monitoring（ MRM）. Methods Into 100 m L water sample,2. 00 m L n- hexane was added and shaken to extract DEHP. After standing for layering,1. 00 μL supernatant was injected for qualitative and quantitative determination by gas chromatography- tandem mass spectrometry（ GC- MS / MS）. Results The detection limit of the method was 0. 00002 mg /L and the recovery rate ranged from 85. 0% to 103. 3% with relative standard deviation of less than 3%. Conclusion This method is convenient,rapid,sensitivity and accurate. It is suitable for the qualitative and quantitative determination of DEHP in water samples.

关 键 词：邻苯二甲酸二(2-乙基己基)酯 气相色谱-串联质谱法 水样 

分 类 号：R115[医药卫生—公共卫生与预防医学]