2009-2015年赣州市疑似预防接种异常反应监测分析  

Surveillance of adverse events following immunization in Ganzhou city,2009-2015

作　　者：钟小荣[1] 陈祥发[1] 张志强[1] 尹帆[1] 刘毅[2] 邓海智[1] 杨静[1] 

机构地区：[1]赣州市疾病预防控制中心,江西赣州341000 [2]于都县疾病预防控制中心,江西于都342300

出　　处：《现代预防医学》2016年第13期2458-2461,2496,共5页Modern Preventive Medicine

摘　　要：目的了解2009-2015年赣州市疑似预防接种异常反应(AEFI)发生特征,评价全市AEFI监测系统运行质量和疫苗接种安全性。方法运用国家AEFI信息管理系统收集个案数据,采用描述性方法进行流行病学分析。结果全市乡报告覆盖率呈逐年上升趋势,7年来共报告AEFI 2 476例,发生率7.15/10万,异常反应发生率1.51/10万剂次。病例以0岁为主,占45.64%;9月报告病例最多,接种后<1天出现反应2 140例,占86.43%;疫苗不良反应发生率居前3位的是百白破、白破和麻风疫苗,临床损害以过敏性皮疹为主。结论全市监测工作取得了非常显著的进步,但监测系统的敏感性有待进一步提高。全市无接种事故,接种服务质量较好。Objective To analysis the adverse events following immunization（AEFI） in Ganzhou city from 2009 to 2015, and evaluate the operation quality and vaccination safety of AEFI system. Methods We collected the AEFI data through the AEFI surveillance system and used the descriptive method to analysis the correlation index. Results There were 2476 cases collected. The reported incidence rate of AEFI was 7. 15/100,000, and the Rare Adverse Reaction was 1.51/100,000. Cases often occurred in September,45.64% cases were under 1 -year -old in 2 140 cases after inoculation 〈 1D reaction. DTAP, DT,and MR had a higher reported incidence rate. Allergic rash was the main clinical damage. Conclusion The AEFI surveillance work of Ganzhou city gets significant progress, however, the sensitivity of the AEFI surveillance system needs further improvement. No vaccination implementation errors of AEFI were reported in Ganzhou city.

关 键 词：疑似预防接种异常反应 监测 分析 

分 类 号：R186[医药卫生—流行病学]