双歧杆菌三联菌(益生菌)对感染性腹泻新生儿生理的 调节机制研究  

Physiological regulatory mechanisms of Bifidobacterium triple bacteria(probiotics) on infectious diarrhea newborn

作　　者：何焱志 黄梅[1] 

机构地区：[1]十堰市妇幼保健院新生儿科,湖北十堰442000

出　　处：《临床与病理杂志》2016年第6期766-770,共5页Journal of Clinical and Pathological Research

摘　　要：目的:探究双歧杆菌三联菌(益生菌)对感染性腹泻新生儿生理的调节作用。方法:选取2013年2月至2015年2月我院收治的130例感染性腹泻新生儿患者为研究对象,将其分为对照组和治疗组,每组65例患者,对照组采用常规性治疗方式,治疗组患者在对照组的基础上采用益生菌进行治疗,对新生儿的生理调节作用进行比较分析。结果:在本次研究中,对照组的治疗总有效率为69.2%,治疗组的治疗总有效率为89.2%,治疗组的治疗效果明显优于对照组,比较结果差异性显著,具有统计学意义(P<0.05)。对照组出现不良反应的患者有10例,不良反应率为15.4%,治疗组出现不良反应的患者有3例,不良反应率为4.6%,两组各项数据比较结果有明显的差异,具有统计学意义(P<0.05)。治疗组的腹泻、呕吐和发热等不良症状消失时间明显小于对照组,比较结果差异性显著,具有统计学意义(P<0.05)。结论:对感染性腹泻新生儿采用益生菌进行辅助治疗,其临床调节作用明显,能有效减少临床不良反应,因此值得临床广泛推广应用。Objective： To explore the physiological regulatory mechanisms of Bifidobacterium triple bacteria （probiotics） on the infectious diarrhea newborn. Methods： 130 cases of infectious diarrhea newborn in our hospital from February 2013 to February 2015 were selected as the study objects, and randomly divided into the control group and treatment group, 65 cases in each group, The control group were given conventional treatment, and the treatment group were given probiotics therapy. The compared and analyzed. Results： In the study, the total physiological regulatory mechanisms on newborn were treatment effective rate in the control group was 69.2%, and treatment group 89.2%, showing that the effect in the treatment group was significantly better than that in the control group （P〈0.05）. There were 10 cases occurring adverse reactions in the control group, with adverse reactions incidence of 15.4%, and 3 cases in the treatment group, with adverse reactions incidence of 4.6%, the difference was significant （P〈0.05）. The disappeared time of diarrhea, vomiting, fever and other adverse symptoms in the treatment group were significantly shorter than that in the control group, with significant differences （P〈0.05）. Conclusion： The adjuvant therapy of probiotics on infectious diarrhea newborn has significant clinical regulatory value. This therapy can effectively reduce the clinical adverse reactions and is worthy of clinical promotion and applications.

关 键 词：双歧杆菌三联菌 感染性腹泻新生 生理调节 

分 类 号：R722.1[医药卫生—儿科]