清热化痰理气方联合左氧氟沙星治疗慢性阻塞性肺疾病患者疗效及对免疫功能的影响  

Effect of Qingre Liqi Huatan prescription combined with levofloxacin in the treatment of curative and effect on immune function

作　　者：马敏[1] 田青[1] 

机构地区：[1]成都市第一人民医院呼吸内科,成都610041

出　　处：《陕西中医》2016年第7期834-835,共2页Shaanxi Journal of Traditional Chinese Medicine

摘　　要：目的:探讨清热化痰理气方联合左氧氟沙星治疗慢性阻塞性肺疾病患者的临床疗效及免疫功能的影响。方法:选取住院治疗的88例COPD患者,随机分为治疗组和对照组,各44例。对照组采用左氧氟沙星治疗,治疗组采用清热化痰理气方联合左氧氟沙星治疗,观察2组患者的临床症状及体征变化,及治疗前后痰量、痰液黏稠度、痰中黏蛋白MUC5AC的含量变化。结果:两组患者治疗后比较,除发热外其余症状均较治疗前有所改善,治疗组的症状改善更为明显。两组患者的祛痰效果均优于治疗前且黏蛋白含量有所降低,治疗组的祛痰效果均优于对照组(P<0.05)。治疗组总有效率为86.4%,高于对照组总有效率68.2%。结论:清热化痰理气方联用左氧氟沙星两种药物对COPD有良好的临床疗效,可有效改善患者气道黏液高分泌状态。Objective：To investigate Qingre Liqi Huatan prescription with Levofloxacin in the treatment of the clinical curative effect of patients with chronic obstructive pulmonary disease and the effect on immune function.Methods：88cases with COPD were analyzed randomly divided into observation group and control group,44 cases in each.The control group used levofloxacin and treatment group used Qingre Liqi Huatan prescription with levofloxacin.observed clinical symptoms,signs of change,sputum volume,the viscidity of sputum,and sputum viscosity of MUC5 AC protein content.Results：Two groups were improved after treatment,the symptoms of the treatment group improved more significantly.Expectorant effect of the two groups were higher than those before treatment and sticky protein content decreased（P〈0.05）.The total effective rate of the treatment group was 86.4%,higher than that of the control group68.2%.Conclusions：Combined use of Qingre Liqi Huatan prescription with levofloxacin has good clinical efficacy in COPD,which effectively improve the patient＇s airway mucus hypersecretion and other clinical symptoms.

关 键 词：肺疾病 慢性阻塞性/中西医结合疗法 祛痰剂/治疗应用 @清热化痰理气方 

分 类 号：R563.9[医药卫生—呼吸系统]