脉平片治疗冠心病心绞痛有效性及安全性的Meta分析  

A Meta-analysis of the Efficacy and Safety of Maiping Tablet on Patients with Unstable Angina

作　　者：闫薇薇[1] 徐卉[1] 秦玲[1] 徐国良[1] 

机构地区：[1]吉林大学第一医院二部,吉林长春130031

出　　处：《中国中医急症》2016年第7期1298-1299,1360,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：吉林省科技厅项目(200905138)

摘　　要：目的应用Meta分析的方法分析脉平片治疗冠心病心绞痛是否有效及安全。方法查阅Cochrane试验资料库(2016年第1期)、Embase(1966年至2016年3月)、Pubmed(1966年至2016年3月)、中国学术文献总库(CNKI)(1979年至2016年3月)、中文科技期刊数据库(1989年至2016年3月)、万方数字期刊库(1981至2016年至3月),根据入选与剔除原则筛选文献、评价文献质量,从文献中提取相关数据,应用Rev Man 5.3软件对提取的数据进行Meta分析。结果初步检索出113篇文献,根据选取标准共有4文献符合。从症状疗效来分析:χ2=4.27,df=3,P=0.23,合并OR=2.45,95%CI[1.50,3.39],Z=3.58(P<0.0003);从心电图疗效来分析:χ2=17.11,df=3,P=0.0007,合并OR=2.30,95%CI[1.56,3.37],Z=4.24(P<0.0001)。结论脉平片治疗冠心病心绞痛在缓解症状及改善心电图方面效果更好无明显不良反应。Objective： To analyze whether Maiping Tablet is effective and safe on angina pectoris through Metaanalysis. Methods： Cochrane Central Register of Controlled Trials （Issuel,2016）,EMbase （1966 to March 2016 ）, Pubmed （ 1966 to March 2016 ）, CNKI （ 1979 to March 2016）, CBM （ 1989 to March 2016 ）, WanFang （ 1981 to March 2016） were searched. According to the principle of selection and elimination,the literature was selected and evaluated. Relevant data was extracted from the literature and analyzed with RevMan 5.3 software. Results： A total of 113 articles were found and 4 of them were finally included. Therapeutic effects of angina pectoris were selected as the study indices： x2=4.27,df=3 ,P= 0.23,and OR=2.45,95%CI [ 1.50,3.39] ,Z=3.58 （P〈 0.0003）. ECG were selected as the study indices ： X2= 17.11, dr=3, P = 0.0007, and OR=2.30,95%CI [ 1.56,3.37 ], Z = 4.24 （P 〈 0.0001 ）. Conclusion： Maiping Tablet on angina pectoris has a better effect in relieving symptoms and improving ECG,with no obvious adverse reaction.

关 键 词：脉平片 冠心病 心绞痛 META分析 

分 类 号：R541.4[医药卫生—心血管疾病]