植物功能基因单核苷酸多态性的研究进展  

Research Progress of Single Nucleotide Polymorphism in Plant Functional Genes

作　　者：张志鹏[1] 王晓玥[1] 黄少雄[1] 张昭[1] 

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所/中草药物质基础与资源利用教育部重点实验室,北京100193

出　　处：《中国农学通报》2016年第20期25-29,共5页Chinese Agricultural Science Bulletin

基　　金：科技基础性工作专项"常用道地药材及其产区的特征;标准及数字化"(2015FY111500)

摘　　要：单核苷酸多态性(SNP)的挖掘和检测目前是一个被广泛关注的研究热点。为能够明晰功能基因SNP和中药材生理活性物质的形成及药材产地之间关系的研究思路,本研究简要归纳了次生代谢功能基因、抗逆性功能基因和农艺性状功能基因等SNP的研究及应用,并对功能基因SNP与植物地理分布关系的研究进行了总结分析。同时,认为借鉴遗传背景清晰的物种挖掘和开发SNP信息用来对其他药用植物开展研究、参照有效成分生源途径较明确的物种对其他药用植物进行相关代谢关键酶基因的探究性研究,是解决数量浩瀚而遗传背景有限的药用植物基因研究的不错的路径,此外提出优良农艺性状或特殊生理现象基因应该成为药用植物功能基因研究的关注点。Single nucleotide polymorphism（SNP） detection and excavation has been a research focus currently.This paper aims to explain the research ideas of the relationship between functional genes and quality ofChinese herbal medicines. It summarized the studies and application of SNP in secondary metabolism genes,resistance genes and agronomic trait genes, as well as analyzed the relationship between functional genes andgeographical distribution. It was considered that developing SNP information of species with clear geneticbackground to conduct research on other medicinal plants, and basing on clear bioactive constituentsbiosynthesis pathway of some species to study other genes of medicinal plants, were good ways to study mostmedicinal plants with limited genetic background. In addition, the gene of good agronomic traits or specialphysiological phenomenon was proposed to be the focus in the function gene research on medicinal plants.

关 键 词：功能基因 SNP 药用植物 

分 类 号：R932[医药卫生—生药学] Q756[医药卫生—药学]