应用皮质类固醇促胎儿成熟对围产期的结局的临床研究  

Clinical Study of the Application of Corticosteroid in Promoting Fetal Maturation in Perinatal Outcome

作　　者：李玲 

机构地区：[1]郁南县人民医院妇产科,广东郁南527100

出　　处：《现代诊断与治疗》2016年第9期1569-1571,共3页Modern Diagnosis and Treatment

摘　　要：目的对应用皮质类固醇促胎儿成熟对围产期结局产生的影响进行研究和分析。方法从我院2013年1月~2014年12月收治的具有早产症状的妊娠期女性中随机选取84例进行研究,并根据其是否应用皮质类固醇分为两组各42例,对照组42例不应用,观察组42例应用,对比两组产妇的围产期结局。结果 （1）经对比,对照组母体肺水肿、尿潴留、感染的发生率分别为45.24%、52.38%和35.71%,明显高于观察组的11.90%、30.95%和9.52%;组间各指标均存在显著差异（P〈0.05）。（2）经对比,对照组新生儿死亡率、呼吸窘迫综合征、脑室内出血的发生率分别为19.05%、23.81%和30.95%,明显高于观察组的2.38%、7.14%和9.52%,组间各指标均存在显著差异（P〈0.05）。结论合理应用皮质类固醇促进胎儿成熟具有显著的临床效果,可减少早产儿死亡率、呼吸窘迫综合征、脑室内出血的发生率,可根据产妇具体情况应用。Objective To study and analyze the effect of corticosteroid on the perinatal outcome.Methods From January 2013 to December, 84 cases of pregnant women with preterm symptoms were randomly selected.Cholesterol is divided into two groups of 42 cases,42 cases of control group were not used, the observation group of 42 cases, compared two groups of maternal and perinatal outcomes.Results（1）By contrast, control group maternal pulmonary edema, urinary retention, the incidence of infection was 45.24%, 52.38% and 35.71% respectively, significantly higher than the observation group of 11.90%, 30.95% and 9.52%; group between each index there are significant difference（P〈0.05）.（2）By contrast, the control group of neonatal mortality, respiratory distress syndrome, intraventricular hemorrhage incidence of 19.05%, 23.81% and 30.95% respectively,significantly higher than the observation group of 2.38%, 7.14% and 9.52%, between groups of each index there are significant difference（P〈0.05）.Conclusion Rational use of corticosteroids to promote fetal maturity has significant clinical effect, can reduce the neonatal mortality rate, respiratory distress syndrome, intraventricular hemorrhage incidence, according to maternal specific application.

关 键 词：皮质类固醇 胎儿成熟 围产期结局 

分 类 号：R714.5[医药卫生—妇产科学]