中西医联合治疗排卵性不孕症的临床疗效及对子宫内膜的影响分析  

The clinical curative effect and the influence analysis on endometrium of integrated traditional and western medicine on treating ovulation infertility

作　　者：孙晓玲[1] 

机构地区：[1]广州中医药大学附属中山市中医院妇产科,广东广州528400

出　　处：《中国医药科学》2016年第9期63-65,共3页China Medicine And Pharmacy

摘　　要：目的：探讨中西医联合治疗排卵性不孕症的临床疗效及对子宫内膜改善状况的分析。方法选择2013年7月～2014年12月来我院妇科门诊174例患者进行不孕不育治疗的为观察对象，随机分为3组。中药组41例，CC组46例，（中药＋CC）组87例。观察并比较患者排卵情况，卵泡大小及子宫内膜发育情况，治疗后随访患者妊娠状况。结果中药组及CC组妊娠率均显著低于（中药＋CC）组，且流产率高于（中药＋CC）组，差异具有统计学意义（P＜0.05）。三组治疗后子宫内膜厚度比较，中药组及（中药＋CC）组比较差异无统计学意义（P＞0.05），两组均显著高于CC组（P＜0.05），而CC组及（中药＋CC）组的排卵率显著高于中药组（P＜0.05）。结论中药制剂联合克罗米芬治疗排卵性不孕症不仅可使患者排卵率得以提高，同时可改善子宫内膜对雌激素的敏感性，二者相辅相成，可在临床推广使用。Objective To explore and discuss the clinical curative effect and the improvement situation analysis on endometrium of integrated traditional and western medicine on treating ovulation infertility. Methods174 patients with infertility treatment in gynecology clinic of my hospital from July 2013 to December 2014 were selected as the observation objects, who were randomly divided into three groups. There were 41 cases of the Chinese medicine group, 46 cases of the CC group, and 87 cases of the Chinese medicines combined with CC group. The ovulation situation, follicular size, and endometrial development in patients were observed and compared, the condition of pregnancy was followed after treatment. Results In the Chinese medicines group and CC group, the pregnancy rate was both significantly lower than that of the Chinese medicines combined with CC group, and the abortion rate was both dramatically higher than that of the Chinese medicines combined with CC group, the differences were statistically significant（P〈0.05）. After treatment, the endometrial thickness of the three groups were compared, there were no statistical differences between the Chinese medicines group and Chinese medicines combined with CC group（P〉0.05）, the endometrial thickness of the two groups was significantly higher than that of the CC group（P〈0.05）, the ovulation rate of the CC group and Chinese medicines combined with CC group was dramatically higher than that of the Chinese medicines group（P〈0.05）.Conclusion Chinese drugs pharmaceutics combined with clomiphene on treating ovulation infertility not only increased the ovulation rate, but also improved the sensitivity of endometrium on estrogen, the two were complementary, which could be promoted and applied in clinic.

关 键 词：中药制剂 补肾活血 克罗米芬(CC) 排卵性不孕症 子宫内膜厚度 雌激素 

分 类 号：R271.19[医药卫生—中医妇科学]