热性惊厥患儿血清白细胞介素-6及10水平变化  

Changes of serum interleukin-6 and interleukin-10 in children with febrile seizures

作　　者：孙文英[1] 李莎莎[1] 闫一兵[1] 

机构地区：[1]聊城市人民医院儿科,山东聊城252000

出　　处：《中华实用诊断与治疗杂志》2016年第7期699-700,共2页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的探讨热性惊厥(febrile seizures,FS)患儿血清白细胞介素(interleukin,IL)-6、IL-10水平变化及意义。方法50例FS患儿为观察组,30例体检健康儿童为对照组,采用ELISA方法检测2组血清IL-6、IL-10水平,并进行比较。结果观察组血清IL-6[(21.81±8.51)ng/L]高于对照组[(4.52±1.46)ng/L],IL-10[(3.06±0.70)ng/L]低于对照组[6.32±1.09)ng/L],差异均有统计学意义(P<0.05)。结论儿童血清IL-6水平升高和IL-10水平降低与FS发作有关。Objective To investigate the changes and the significances of serum levels of interleukin （IL）-6 and IL-10 in children with febrile seizures （FS）. Methods The levels of IL-6 and IL-10 were detected by ELISA technique and compared between 50 children with FS （observation group） and 30 healthy volunteers （control group）. Results The IL-6 level was significantly higher and IL-10 was significantly lower in observation group （（21. 81±8. 51）, （3. 06 ± 0.70） ng/L） than those in control group （（4.52±1.46）, （6. 32±1.09） ng/L） （P〈0.05）. Conclusion The increased IL-6 and decreased IL-10 levels are correlated with the attack of FS.

关 键 词：热性惊厥 白细胞介素-6 白细胞介素-10 

分 类 号：R720.597[医药卫生—急诊医学]