不同再灌注时间对Q波型急性心肌梗死患者心室重构以及左心功能的影响  

Impact of different reperfusion time window on ventricular remodeling and left ventricular function in patients with Q-wave acute myocardial infarction

作　　者：曾振宇[1] 周文霞[2] 

机构地区：[1]四川省中西医结合医院急诊科,成都610000 [2]四川大学华西医院超声心动图室

出　　处：《陕西医学杂志》2016年第7期804-806,共3页Shaanxi Medical Journal

基　　金：四川省中医药管理局科研项目(2014B091)

摘　　要：目的:探讨不同再灌注时间对Q波型急性心肌梗死患者心室重构以及左心功能的影响。方法:选取Q波型急性心肌梗死患者394例,根据再灌注时间的不同分A、B、C三组,其中A组170例灌注时间t<12h;B组118例灌注时间12h<t≤24h;C组106例灌注时间24h<t≤72h。对患者治疗前、住院期间心功能以及心脏形态情况进行记录。结果:治疗后三组间截断灌注异常改善情况具有统计学差异,越早采取再灌注患者截断灌注异常改善程度越明显。各组间治疗后短轴缩短率、左心室舒张末期直径以及LVEF存在统计学差异,越早采取再灌注的患者短轴缩短率、左心室舒张末期直径以及LVEF改善程度较治疗前越明显。结论:尽早进行再灌注治疗可明显改善Q波型急性心肌梗死患者心功能,且对患者心室重构具有调节作用。Objective：To investigate the impact of different reperfusion time window on ventricular remodeling and left ventricular function in patients with Q-wave acute myocardial infarction.Methods：394patients with initial Q-wave myocardial infarction were divided into A,B and C three groups according to the different reperfusion time window conducted into the treatment.The reperfusion time window of the three groups were less than12 hin group A,12ht≤24hin group B,24ht≤72hin group C.The ventricular remodeling and left ventricular function were investigated before and after treatment.Results：The truncated perfusion abnormalities of the three groups were improved after treatment and with significant difference compared to that of before.The earlier reperfusion was taken,the better degree of perfusion abnormalities was achieved.The fractional shortening,left ventricular end-diastolic diameter and LVEF of each group was significantly different from that of treatment before,which showed that patients were taken the earlier reperfusion,the improvement of left ventricular end-diastolic diameter and LVEF was more obvious than before.Conclusion：The early reperfusion therapy can significantly improve heart function in patients with Q-wave acute myocardial infarction,and the ventricular remodeling is also improved.

关 键 词：心肌梗塞/病理生理学 心室重构 心肌再灌注 

分 类 号：R542.2[医药卫生—心血管疾病]