有机磺酰氯参与的磺酰化及脱磺酰化反应  

Progress on the Sulfonylation and Desulfonylative Reactions of Sulfonyl Chlorides

作　　者：傅颖[1] 赵兴玲[1] 侯博[1] 

机构地区：[1]西北师范大学化学化工学院,兰州730070

出　　处：《有机化学》2016年第6期1184-1196,共13页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21262030;20962017)资助项目~~

摘　　要：作为一类活泼的亲电试剂,有机磺酰氯参与的脱磺酰化偶联反应已经发展成为一个新的研究热点.在适当的温度以及钯等过渡金属络合物的催化下,磺酰氯可以和多种亲核试剂发生脱磺酰化偶联反应,并在一些重要有机合成反应中显示出良好的应用前景.有鉴于此,特就过渡金属催化下磺酰氯的脱磺酰化交叉偶联的研究进展进行简要的评述,并与相应的磺酰化反应进行对照,以其找出脱磺酰化偶联的关键因素,为以后的相关研究提供参考.Being an active class of electrophiles, the desulfitative cross-couplings of sulfonyl chlorides has emerged as a hot issue nowadays. Under suitable temperature and transitional metal catalysis, sulfonyl chlorides efficiently cross-coupled with a wide range of nucleophiles which were potential in several important organic synthesis. The transitional metal catalyzed desulfitative coupling reactions of sulfonyl chlorides are briefly reviewed and are compared with their corresponding sulfonylation reaction in order to find the key factors that determine desulfonation and further providing reliable proposal for future researches.

关 键 词：磺酰氯 交叉偶联 脱磺酰化 

分 类 号：O621.25[理学—有机化学]