Syntheses, Structures and Anticancer Activities of Three 4(3H)-Quinazolinone Cd(Ⅱ) Complexes  

Syntheses, Structures and Anticancer Activities of Three 4(3H)-Quinazolinone Cd(Ⅱ) Complexes

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作  者:李石雄 廖蓓玲 银秀菊 张金恒 蒋毅民 

机构地区:[1]College of Environment and Energy, South China University of Technology [2]College of Chemistry and Pharmacy, Guangxi Normal University [3]College of Chemistry and Biological Engineering, Hechi University

出  处:《Chinese Journal of Structural Chemistry》2016年第6期863-871,共9页结构化学(英文)

基  金:Supported by the Guilin scientific research and technological development program(No.20110330);the project of education department of Guangxi province(No.YB2014331);the Natural Science Foundation of Guangxi Province(2014GXNSFAA118035)

摘  要:The title complexes based on 4(3H)-quinazolinone ligand have been synthesized and characterized by elemental analysis, IR spectrum and single-crystal X-ray diffraction analysis.Complex 1 belongs to the triclinic system, space group P1, with a = 6.5392(3), b = 7.4402(5), c =10.3397(7) ?, α = 83.204(5), β = 75.465(5), γ = 86.075(5)° and V = 483.88(5) ?~3. Complex 2 is of orthorhombic system, space group Pbca, with a = 10.1294(3), b = 7.6747(5), c = 23.8171(15) ? and V = 1849.1(4) ?~3. Complex 3 belongs to the orthorhombic system, space group Pbca, with a =12.7188(2), b = 6.66582(9), c = 25.6987(6) ? and V = 2178.77(5) ?~3. The complex structures are affected by the synthesis conditions.The title complexes based on 4(3H)-quinazolinone ligand have been synthesized and characterized by elemental analysis, IR spectrum and single-crystal X-ray diffraction analysis.Complex 1 belongs to the triclinic system, space group P1, with a = 6.5392(3), b = 7.4402(5), c =10.3397(7) ?, α = 83.204(5), β = 75.465(5), γ = 86.075(5)° and V = 483.88(5) ?~3. Complex 2 is of orthorhombic system, space group Pbca, with a = 10.1294(3), b = 7.6747(5), c = 23.8171(15) ? and V = 1849.1(4) ?~3. Complex 3 belongs to the orthorhombic system, space group Pbca, with a =12.7188(2), b = 6.66582(9), c = 25.6987(6) ? and V = 2178.77(5) ?~3. The complex structures are affected by the synthesis conditions.

关 键 词:complex 4(3H)-quinazolinone anticancer 

分 类 号:O641.4[理学—物理化学] TQ460.1[理学—化学]

 

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