钛板重建下颌骨体部缺损的生物力学变化  

Biomechanical analysis of mandibular body reconstruction using titanium plate

作　　者：陈彪[1] 范戌辉[1] 刘耀强[1] 岳磊[1] 张睿[1] 屈鹏飞[1] 贾志宇[1] 赵云转[1] 杨威[1] 

机构地区：[1]河北医科大学第二医院口腔颌面外科,河北省石家庄市050005

出　　处：《中国组织工程研究》2016年第30期4413-4418,共6页Chinese Journal of Tissue Engineering Research

基　　金：河北省卫生厅科研基金项目(20150256)~~

摘　　要：背景:三维有限元在口腔领域应用广泛,但关于下颌骨体部缺损钛板重建的三维有限元研究不多。目的:三维有限元分析钛板重建下颌骨体部缺损的生物力学特点。方法:建立下颌骨体部缺损双皮质钛钉钛板重建的三维有限元模型,模拟正常咬合状态,在右侧下颌骨第一磨牙咬合面中央窝垂直加载200 N的载荷,分析下颌骨、钛钉、钛板的应力分布和最大位移。结果与结论:(1)模拟咀嚼运动加载后下颌骨的应力在下颌体和下颌支部比较集中,其中应力集中比较明显的部位是下颌支的前后缘和下颌骨的下缘,下颌骨后缘的应力小于下颌骨前缘的应力,钛板固定和骨质接触部位也出现应力集中;(2)双皮质钛钉近螺帽处应力值最大,钛钉和钛板接触部位出现应力集中现象;(3)下颌骨升支部钛钉的最大应力值大于缺损前端钛钉最大应力值;(4)钛板的应力集中部位主要为钛钉固定部位,钛板上缘和下缘的应力峰值主要集中在下颌骨缺损前端和钛钉接触区以及下颌骨升支的钛钉接触区;(5)钛板重建下颌骨体部缺损后位移比较容易发生在缺损前端下颌骨和钛板接触部位;(6)结果表明,下颌骨体部缺损双皮质钛钉钛板固定重建相对比较稳定,下颌角前端的钛板比较容易发生断裂。BACKGROUND： Three-dimensional finite element has been widely used in the oral cavity field, but little is reported on the three-dimensional finite element reconstruction of the mandibular body using titanium plate. OBJECTIVE： To study the biomechanical characteristics of reconstructing the mandibular body using titanium plate. METHODS： We established a three-dimensional finite element model of mandibular body defect undergoing reconstruction using bicortical titanium screws and titanium plate. Under the simulated normal occlusion state, a 200 N vertical load was added to the central fossa of the occlusal surface of the right mandible first molar. Then, stress distribution and maximum displacement of the mandible, titanium screw, and titanium plate were analyzed. RESULTS AND CONCLUSION： Under the simulated normal occlusion state, mandible stress was concentrated in the mandibular body and mandibular branch, especially in the anterior and posterior edges of the mandibular branch and the lower edge of the mandible. The stress in the posterior edge of the mandible was lower than that in the anterior edge of the mandible, and moreover, the contact site between the titanium plate and the mandible also presented a concentration of stress. The maximum stress of the bicortical titanium screws appeared near the screw cap, and the stress was also concentrated at the contact site between the titanium screw and the titanium plate. The maximum stress of the titanium screw at the ascending branch of the mandible was higher than that of the titanium screw at the anterior end of the defect. For the titanium plate, the stress was mainly concentrated at the fixed site of the titanium screws; the peak stress of the anterior and posterior edges of the titanium plate was found at the contact ,site between the anterior end of mandibular defect and the titanium stress as well as between the ascending branch of the mandible and the titanium screw. After mandibular body reconstruction using the titanium plate, a displacement was l

关 键 词：下颌骨 钛 内固定器 有限元分析 生物力学 组织工程 生物材料 骨生物材料 钛板 重建 下颌骨体部缺损 三维有限元 生物力学分析 

分 类 号：R318[医药卫生—生物医学工程]