高原驻训官兵肝脏脂肪变性与缺氧等关系探讨  

Correlation offatty liver with hypobaric hypoxia in plateau encamping soldiers for short time

作　　者：丰惠[1] 贾宁阳[1] 刘燕[2] 李长英[2] 沈海明[3] 李治群[4] 王洪武[5] 

机构地区：[1]第二军医大学附属东方肝胆外科医院放射科,上海200438 [2]解放军42医院,四川夹江614100 [3]中国民航大学航空医学研究所,天津300300 [4]海南医学院附属医院影像科,海南海口570102 [5]华中科技大学同济医学院附属同济医院感染科,湖北武汉430030

出　　处：《东南国防医药》2016年第3期259-261,共3页Military Medical Journal of Southeast China

摘　　要：目的探讨高原缺氧环境对驻训官兵肝脏代谢的影响。方法选择某部2013年4-8月进入西藏高原驻训士兵共计39例,分别于驻训前后进行肝脏CT扫描、血脂三项及血氧饱和度测定。结果驻训后受检者肝CT值、血氧饱和度降低,总胆固醇、甘油三脂均有不同程度升高,与驻训前相比差异均有统计学意义(P<0.05);低密度脂蛋白驻训前后差异不存在统计学意义(P>0.05);驻训后男女间肝CT值、驻训前后总胆固醇及低密度脂蛋白差异存在统计学意义(P<0.05),而在驻训前男女间肝CT值、驻训前后甘油三脂、血氧饱和度差异不存在统计学意义(P>0.05)。驻训前肝CT值与血脂三项呈负相关(分别为:r=-0.812、-0.731、-0.769,均P<0.01)。驻训后CT值与血脂三项呈负相关(分别为:r=-0.791、-0.759、-0.700,均P<0.01),与血氧饱和度呈正相关(r=0.516,P<0.01)。结论高原缺氧环境对驻训官兵肝脏代谢有影响,可引起肝脏脂肪变性及血脂升高,男性影响大于女性。Objective To investigate the effect of hypobaric hypoxia on liver in encamping soldiers. Methods 39 encamping soldiers were chosen from April to August 2013 to participate in the plateau as research subjects, monitoring the changes of CT scan, blood fat, blood oxygen saturation before and after encamping. Results Both the level of CT value and blood oxygen saturation was de？creased;there was significant difference before and after encamping. Both the level of total cholesterol and triglyceride was increased;there was significant difference before and after encamping. There was no significant difference in low density lipoprotein before and af？ter encamping （ P〉0.05） . There was significant difference among different genders in CT value after encamping, total cholesterol and low density lipoprotein before and after encamping. There was no significant difference among different genders in CT value before en？camping, triglyceride and low density lipoprotein before and after encamping. The CT value was significantly correlated with the level of blood fat both before and after encamping （ r=-0.812,-0.731,-0.769;r=-0.791,-0.759,-0.700） . The CT value was significantly correlated with the level of blood oxygen saturation after encamping （r=0.516）. Conclusion Hypobaric hypoxia can cause the fatty degeneration and increase the level of blood fat in encamping soldiers, which was more obvious on males.

关 键 词：高原 缺氧 脂肪肝 高脂血症 

分 类 号：R825.7[医药卫生—临床医学]