急性百草枯中毒的救治分析  

作　　者：花保安[1] 金磊[1] 姜波[1] 吴化奎[1] 

机构地区：[1]安徽省淮南市第一人民医院重症医学科,232001

出　　处：《浙江临床医学》2016年第8期1489-1491,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨急性百草枯（PQ）中毒的临床特点、救治方法及预后，以期提高急性PQ中毒的救治成功率。方法对16例口服PQ自杀中毒患者的临床资料进行回顾性分析。结果16例患者中存活10例，死亡6例，救治成功率62．5％。结论血液灌流（HP）加持续肾脏替代治疗（CRRT）及抗炎症反应等综合治疗方法对救治急性口服PQ中毒疗效较好；服毒量大、急性呼吸衰竭、多器官功能障碍综合征（MODS）是制约急性PQ中毒存活率的关键因素；外周血白细胞计数〉20．0×109／L提示预后极差。Objective To explore clinical characterization, treatment, and prognosis of acute paraquat poisoning for improving the success rate of treat and care of acute paraquat poisoning. Methods A retrospective analysis was performed according to the clinical data from sixteen patients orally with paraquat. Results Ten of sixteen patients survived, and six of them died, the success rate of treat and care was 62.5%. Conclusions The curative effect was better for the patients with orally intaking of paraquat by treatment of hemoperfusion, combining continuous renal replacement therapy and anti-inflammatory response. However, the critical factors of success rate were limited by overdosed poisoning, acute respiratory failure, and multiple organ dysfunction syndrome. The count of white blood cells is more than 20.0 × 109/L implying poor prognosis.

关 键 词：百草枯中毒 血液灌流 持续肾脏替代治疗 综合治疗 

分 类 号：R595.4[医药卫生—内科学]