探讨阿昔洛韦联合丙种球蛋白治疗重症水痘的疗效  

An Discussion of Efficacy of Acyclovir Combined with Gamma Globulin in the Treatment of Severe Varicella

作　　者：郑军[1] 戴光辉[2] 

机构地区：[1]常德职业技术学院医学系皮肤性病学教研室,湖南常德415000 [2]常德职业技术学院附属第二医院皮肤性病科,湖南常德415000

出　　处：《中国医药指南》2016年第18期129-130,共2页Guide of China Medicine

摘　　要：目的观察并分析阿昔洛韦与丙种球蛋白联合疗法在重症水痘的治疗中的应用效果。方法选取80例重症水痘患儿,依据治疗方法的不同将其列入观察组与对照组,各40例。对照组使用阿昔洛韦进行治疗,在对照组基础上,观察组加用丙种球蛋白,观察两组患者的临床治疗效果。结果两组退热的时间、疱疹结痂的时间和总住院时间比较,差异均有统计学意义(P<0.05);两组均不存在严重的不良反应。结论在重症水痘的治疗中,阿昔洛韦与丙种球蛋白联合疗法安全有效,属于一种行之有效的临床治疗方法,可推广。Objective To observe and analyze the effects of acyclovir combined with gamma globulin in the treatment of severe varicella. Methods 80 cases of children with severe varicella were selected, according to different treatment methods they were included in the observation group and the control group, 40 patients in each group. Control group was treated with acyclovir in the control group, based on which the observation group added gamma globulin for treatment. Results The defervesce time, escharosis time and total hospital stay time in two groups had differences which were statistically significant（P〈0.05）; both two groups did not occur serious adverse reactions. Conclusion In the treatment of children varicella, the combination therapy of Acyclovir and gamma globulin is safe and effective, which is an effective clinical treatment and can be promoted.

关 键 词：阿昔洛韦 丙种球蛋白 重症水痘 效果 

分 类 号：R511.5[医药卫生—内科学]