抗凝血酶-Ⅲ检测在慢性肾小球肾炎与泌尿系感染中的比较分析  

Evaluation on AT-m in patients with chronic glomerulonephritis and urinary tract infection

作　　者：赵熹君 潘小萍 段美庆[2] 

机构地区：[1]内蒙古自治区人民医院检验科,呼和浩特010017 [2]内蒙古医科大学附属医院检验科,呼和浩特010050

出　　处：《国际免疫学杂志》2016年第4期358-360,共3页International Journal of Immunology

摘　　要：目的 通过抗凝血酶Ⅲ（AT-Ⅲ）的检测,探讨其在慢性肾小球肾炎和泌尿系感染患者中的诊断价值.方法 采用内蒙古自治区人民医院确诊的慢性肾小球肾炎患者、泌尿系感染患者和健康体检者各126例抗凝全血标本,按说明操作CS-5100凝血分析仪,测定三组标本AT-Ⅲ数据.结果 确诊的各126例慢性肾小球肾炎和泌尿系感染抗凝全血标本的AT-Ⅲ检测结果经t检验分析表明,慢性肾小球肾炎组与泌尿系感染组、对照组AT-Ⅲ检测结果比较在统计学上均存在差异（t=7.331,P＜0.05;t=7.297,P ＜0.05）;而泌尿系感染组与对照组AT-Ⅲ检测结果差异无统计学意义（t=1.216,P＞0.05）.结论 AT-Ⅲ的检测在慢性肾小球肾炎组中具有一定的临床诊断意义.Objective To explore the anti-thrombin Ⅲ（AT-Ⅲ） diagnostic value in patients with chronic glomerulonephritis and urinary tract infection by its detection.Method The AT-Ⅲ results of anticoagulation blood samples were collected from 126 patients with chronic glomerulonephritis,126 patients with urinary tract infection and 126 healthy control in Inner Mongolia Autonomous Region People＆#39;s hospital,the samples were analyzed by CS5100 coagulation analyzer according to these instructions.Result There are significantly difference between chronic glomerulonephritis group,urinary tract infection group and control group in AT-Ⅲ detection （t =7.331 P 〈 0.05;t =7.297 P 〈 0.05）;But there is no difference between urinary tract infection group and control group in AT-Ⅲ detection （t =1.216 P 〉 0.05）.Conclusion The detection of AT-Ⅲ may be have clinical significance in the diagnosis of chronic glomerulonephritis.

关 键 词：慢性肾小球肾炎 泌尿系感染 抗凝血酶Ⅲ 

分 类 号：R277.523.1[医药卫生—中医学]